Evidence map›Paper›PMID 29715717›Full record

ArticleBiomolecules & therapeutics2018

Antiviral and Anti-Inflammatory Activities of Pochonin D, a Heat Shock Protein 90 Inhibitor, against Rhinovirus Infection.

Jae-Hyoung Song, Aeri Shim, Yeon-Jeong Kim, Jae-Hee Ahn, Bo-Eun Kwon, Thuy Trang Pham, Jongkook Lee, Sun-Young Chang, Hyun-Jeong Ko

Abstract read
In one paragraph

Article in Biomolecules & therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jae-Hyoung SongCollege of Pharmacy, Kangwon National University, Chuncheon 24341, Republic of Korea.
Aeri ShimCollege of Pharmacy, Kangwon National University, Chuncheon 24341, Republic of Korea.
Yeon-Jeong KimCollege of Pharmacy, Inje University, Gimhae 50834, Republic of Korea.
Jae-Hee AhnCollege of Pharmacy, Kangwon National University, Chuncheon 24341, Republic of Korea.
Bo-Eun KwonCollege of Pharmacy, Kangwon National University, Chuncheon 24341, Republic of Korea.
Thuy Trang PhamCollege of Pharmacy, Kangwon National University, Chuncheon 24341, Republic of Korea.
Jongkook LeeCollege of Pharmacy, Kangwon National University, Chuncheon 24341, Republic of Korea.
Sun-Young ChangCollege of Pharmacy, Ajou University, Suwon 16499, Republic of Korea.
Hyun-Jeong KoCollege of Pharmacy, Kangwon National University, Chuncheon 24341, Republic of Korea.
Kangwon National University · KRAjou University · KRInje University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human rhinoviruses (HRV) are one of the major causes of common cold in humans and are also associated with acute asthma and bronchial illness. Heat-shock protein 90 (Hsp90), a molecular chaperone, is an important host factor for the replication of single-strand RNA viruses. In the current study, we examined the effect of the Hsp90 inhibitor pochonin D,

Indexed as

Anti-inflammatoryAntiviral activityHeat-shock protein 90Pochonin DRrhinovirus

Identifiers

PMID29715717
PMCPMC6254639
OpenAlexW2800699200

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.