Evidence map›Paper›PMID 29715609›Full record

ArticleJournal of affective disorders2018

The impact of pre- and perinatal factors on psychopathology in adulthood.

Cecilia A Essau, Satoko Sasagawa, Peter M Lewinsohn, Paul Rohde

Abstract read
In one paragraph

Article in Journal of affective disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Inflammatory mechanisms contribute to long-term cognitive deficits induced by perinatal asphyxia via interleukin-1.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Cecilia A EssauDepartment of Psychology, Roehampton University, London SW15 4JD, UK. Electronic address: c.essau@roehampton.ac.uk.
Satoko SasagawaFaculty of Human Sciences, Mejiro University, Tokyo 161-8539, Japan.
Peter M LewinsohnOregon Research Institute, Eugene, OR 97403-1983, USA.
Paul RohdeOregon Research Institute, Eugene, OR 97403-1983, USA.
Oregon Research Institute · USMejiro University · JPUniversity of Roehampton · GB

Funding

NATURAL HISTORY OF DEPRESSION IN ADOLESCENTSR01MH050522 · NIMH · OREGON RESEARCH INSTITUTE · PI LEWINSOHN, PETER M. · 1993 to 2001
$121k
ADOLESCENT DEPRESSION: PREVALENCE &PSYCHOSOCIAL ASPECTSR01MH040501 · NIMH · OREGON RESEARCH INSTITUTE · PI LEWINSOHN, PETER M. · 1986 to 1990
–
NIMH NIH HHS R01 MH040501NIMH NIH HHS R01 MH050522
6 · The paper itself

Abstract

backgroundThere is considerable evidence that pre- and post-natal factors are associated with a wide range of psychopathology in offspring during childhood and adolescence.

objectiveThe main aims of the present study were to examine the associations between pre- and perinatal factors and psychopathology in offspring during adulthood, and to explore whether family factors (i.e., family cohesion, mother's social support, and father's social support) mediate these relationships.

methodInformation on pre- and perinatal events was collected from biological mothers of the participants (N = 315) when they were between 14 and 18 years who were then followed up until they reached age 30.

resultsMaternal obstetric history and illness during first year were significant predictors of offspring anxiety disorder. Maternal emotional health predicted offspring affective disorder. Difficult delivery and breast feeding predicted disruptive disorder. The relationship between maternal obstetric history/emotional health and anxiety/affective disorder was no longer significant after controlling for family cohesion. LIMITATIONS: The information was based on maternal recall when their offspring were between 14 and 18 years which may be subjected to recall bias.

conclusionThe association between pre- and postnatal factors and psychopathology of offspring during adulthood is mediated by familial factors.

Indexed as

AdolescentAdultAdult ChildrenBreast FeedingFamilyFemaleHumansMaleMothersPregnancyPrenatal Exposure Delayed EffectsPsychopathologyRisk FactorsYoung AdultDepressionOffspringPostnatal factorsPrenatal factorsPsychopathology

Identifiers

PMID29715609
PMCPMC6127869
OpenAlexW2799426733

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.