Evidence map›Paper›PMID 29715538›Full record

ArticleBehavioural brain research2018

Age- and sex-dependent effects of methamphetamine on cognitive flexibility and 5-HT

Emily R Hankosky, Sara R Westbrook, Rachel M Haake, Jari Willing, Lori T Raetzman, Janice M Juraska, Joshua M Gulley

Abstract read
In one paragraph

Article in Behavioural brain research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Emily R HankoskyDepartment of Psychology, University of Illinois, Urbana-Champaign, 603 E. Daniel St., Champaign, IL, 61820, USA; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 S. Limestone, Lexington, KY, 40536, USA. Electronic address: e.hankosky@uky.edu.
Sara R WestbrookDepartment of Psychology, University of Illinois, Urbana-Champaign, 603 E. Daniel St., Champaign, IL, 61820, USA. Electronic address: srwestb2@illinois.edu.
Rachel M HaakeDepartment of Psychology, University of Illinois, Urbana-Champaign, 603 E. Daniel St., Champaign, IL, 61820, USA. Electronic address: rhaake22@email.unc.edu.
Jari WillingDepartment of Psychology, University of Illinois, Urbana-Champaign, 603 E. Daniel St., Champaign, IL, 61820, USA. Electronic address: jwillin@illinois.edu.
Lori T RaetzmanNeuroscience Program, University of Illinois, Urbana-Champaign, 505 S. Goodwin Avenue, Urbana, IL, 61801, USA; Molecular and Integrative Physiology, University of Illinois, Urbana-Champaign, 505 S. Goodwin Avenue, Urbana, IL, 61801, USA. Electronic address: raetzman@life.illinois.edu.
Janice M JuraskaDepartment of Psychology, University of Illinois, Urbana-Champaign, 603 E. Daniel St., Champaign, IL, 61820, USA; Neuroscience Program, University of Illinois, Urbana-Champaign, 505 S. Goodwin Avenue, Urbana, IL, 61801, USA. Electronic address: jjuraska@illinois.edu.
Joshua M GulleyDepartment of Psychology, University of Illinois, Urbana-Champaign, 603 E. Daniel St., Champaign, IL, 61820, USA; Neuroscience Program, University of Illinois, Urbana-Champaign, 505 S. Goodwin Avenue, Urbana, IL, 61801, USA. Electronic address: jgulley@illinois.edu.
University of Illinois Urbana-Champaign · USUniversity of Kentucky · US

Funding

Mechanisms of amphetamine-induced plasticity in adolescents compared to adultsR01DA029815 · NIDA · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI GULLEY, JOSHUA M · 2011 to 2015
$1.5M
Methamphetamine effects on cognition and 5-HT receptors in orbitofrontal cortexF31DA036330 · NIDA · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI HANKOSKY, EMILY RUTH · 2014 to 2015
$86k
NIDA NIH HHS F31 DA036330NIDA NIH HHS R01 DA029815
6 · The paper itself

Abstract

Adolescents and females experience worse outcomes of drug use compared to adults and males. This could result from age- and sex-specific consequences of drug exposure on brain function and cognitive behavior. In the current study, we examined whether a history of intravenous methamphetamine (METH) self-administration impacted cognitive flexibility and 5-HT

Indexed as

Administration, IntravesicalAgingAmphetamine-Related DisordersAnimalsCentral Nervous System StimulantsDiscrimination, PsychologicalExecutive FunctionFemaleInterneuronsMaleMethamphetaminePrefrontal CortexRats, Sprague-DawleyReceptor, Serotonin, 5-HT2CReversal LearningSelf AdministrationCentral Nervous System StimulantsMethamphetamineReceptor, Serotonin, 5-HT2CAdolescenceCognitive flexibilityOrbitofrontal cortexParvalbuminSerotonin-2C receptorsSex differences

Identifiers

PMID29715538
PMCPMC5993617
OpenAlexW2801457318

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.