ArticlePloS one2018
Mobility limitations related to reduced pulmonary function among aging people with chronic obstructive pulmonary disease.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Association of lung function with functional limitation in older adults: A cross-sectional study.PloS one · 2021Trial
- Associations of spirometricFrontiers in public health · 2026Article
- Disability in Older Adults with COPD: Prevalence, Assessment, and Influencing Factors - A Scoping Review.Clinical interventions in aging · 2026Article
- Does engagement in healthy ageing differ according to gender? Community-based cross-sectional study.Journal of health, population, and nutrition · 2025Article
- From Breathlessness to Better Living: Transforming COPD Care with Home-based Pulmonary Rehabilitation.Rambam Maimonides medical journal · 2025Article
- Dynamic changes in quality of life in older patients with chronic obstructive pulmonary disease: a 7-year follow up.Health and quality of life outcomes · 2024Article
- Olfactory decline develops in parallel with frailty in older US adults with obstructive lung diseases.International forum of allergy & rhinology · 2024Article
- Associations of sarcopenia with peak expiratory flow among community-dwelling elderly population: based on the China Health and Retirement Longitudinal Study (CHARLS).European geriatric medicine · 2024Article
- Peak Expiratory Flow Predicts Incident Dementia in a Representative Sample of U.S. Older Adults: The National Health and Aging Trends Study (NHATS).The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Relation of incident chronic disease with changes in muscle function, mobility, and self-reported health: Results from the Health and Retirement Study.PLOS global public health · 2022Article
- Article
- Statistical analysis plan for "A randomised, controlled study to evaluate the effects of switching from cigarette smoking to using a tobacco heating product on health effect indicators in healthy subjects".Contemporary clinical trials communications · 2020Article
- 2011 GOLD Stages of COPD: Transitions, Predictor Factors and Comparison with 2017 GOLD Stages.International journal of chronic obstructive pulmonary disease · 2020Article
- The prognosis of pre-frail chronic obstructive pulmonary disease patients for hospitalizations and mortality depends on their level of functional physical performance.Chronic respiratory diseaseArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic obstructive pulmonary disease (COPD) is a major cause of disability. We aimed to analyse the impact of reduced pulmonary function on non-respiratory impairments and mobility activity limitations in an elderly population with COPD and to elucidate which specific limitations on mobility are related to reduced pulmonary function.
methodsCross-sectional study of 110 patients with COPD, recruited from public and university hospital. The effect of impaired pulmonary function on the risk of non-respiratory impairments and mobility limitations was analysed using validated measures, including: the 6-Minute Walk Test (6MWT), skeletal muscle strength, the Short Physical Performance Battery (SPPB), and self-reported mobility questionnaire. Multivariate analysis was used to control for confounders such as age, sex, height, education, and cigarette smoking.
resultsGreater impairment of pulmonary function was associated with less distance walked during the 6MWT, poorer SPPB scores, and greater risk of self-reported mobility limitations (p<0.05). Lower forced expiratory volume in 1 s was also associated with a greater risk of limitations in carrying items under 10 pounds (4.54 kg), walking alone up and down a flight of stairs, and walking two or three neighbourhood blocks. There was no clear statistical relationship between pulmonary function impairment and skeletal muscle strength.
conclusionsImpaired pulmonary function was associated with the 6MWT score and limitations on performance-based and self-reported mobility activities, but not with skeletal muscle strength among elderly COPD patients.
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