Evidence map›Paper›PMID 29713985›Full record

ArticleDigestive diseases and sciences2018

Advanced Age Does Not Negatively Impact Health-Related Quality of Life in Inflammatory Bowel Disease.

Lilani P Perera, Sanjay Bhandari, Roy Liu, Corinne Guilday, Yelena Zadvornova, Kia Saeian, Daniel Eastwood

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Digestive diseases and sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Mapping from SIBDQ to EQ-5D-5L for patients with inflammatory bowel disease.The European journal of health economics : HEPAC : health economics in prevention and care · 2024
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Lilani P PereraDirector Inflammatory Bowel Disease Center, Aurora Healthcare, 975 Port Washington Rd, Grafton, WI, 53024, USA. Lilani.Perera@aurora.org.
Sanjay BhandariDivision of General Internal Medicine, Milwaukee, WI, USA.
Roy LiuDivision of Internal Medicine, University of Utah, Salt Lake City, UT, USA.
Corinne GuildayWashington University, St. Louis, MO, USA.
Yelena ZadvornovaDivision of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, WI, USA.
Kia SaeianDivision of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, WI, USA.
Daniel EastwoodDivision of Biostatistics, Medical College of Wisconsin, Milwaukee, WI, USA.
Medical College of Wisconsin · USAurora Health Care · USUniversity of Utah · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealth-related quality of life (HRQoL) is significantly impacted in patients with inflammatory bowel disease (IBD). Many studies have assessed HRQoL in patients of all ages, and few focus on the elderly.

aimTo determine the influence of advanced age (> 65 years) and age at diagnosis on patients with IBD.

methodsThis is a retrospective study of prospectively collected data from a single IBD tertiary referral center. Patients had disease activity indices [Harvey-Bradshaw index (HBI), Ulcerative Colitis Disease Activity Index (UCDAI), and Short Inflammatory Bowel Disease Questionnaire (SIBDQ)] recorded during every clinic visit. Three groups of patients: > 65 years, 41-64 years, and < 40 years with > 5 SIBDQ entries were included. Influence of disease type, disease duration, extent of involvement, and comorbidities such as cardiovascular (CV) disease, pulmonary disease, diabetes mellitus (DM), and psychological disorders were noted as confounders. Statistical analysis was performed using ANOVA, Pearson correlation, and logistic regression model.

resultsDisease severity indices significantly affected SIBDQ score in both Crohn's disease (CD) and ulcerative colitis (UC) (p < 0.001 for HBI in CD, p < 0.001 UCDAI in UC). Disease extent (p = 0.011) and psychological disorders (p < 0.001) significantly affected SIBDQ score in CD. Chronological age, age at diagnosis, disease duration, number of clinic visits, CV disease, pulmonary disease, and DM were not significant predictors of SIBDQ score (p > 0.05).

conclusionsHRQoL was negatively influenced by disease extent and psychological disorders in CD but not in UC patients. Advanced age was not a predictor of poor HRQoL in both CD and UC.

Indexed as

Quality of LifeAdultAgedAge FactorsAgingColitis, UlcerativeComorbidityCrohn DiseaseFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsSeverity of Illness IndexSurveys and QuestionnairesElderlyHealth-related quality of lifeInflammatory Bowel DiseaseShort Inflammatory Bowel Disease Questionnaire

Identifiers

PMID29713985
OpenAlexW2802912282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.