Evidence map›Paper›PMID 29713890›Full record

Trial reportClinical oral investigations2019

Pain perception following epithelialized gingival graft harvesting: a randomized clinical trial.

Lorenzo Tavelli, Andrea Ravidà, Muhammad H A Saleh, Bartosz Maska, Fernando Suárez-López Del Amo, Giulio Rasperini, Hom-Lay Wang

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Clinical oral investigations, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 45 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 10 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03584906 nacompletednot on this map

Comparison of Graft Quality and Patient Morbidity Following Four Different Connective Tissue Graft Harvesting Techniques. A Randomized Controlled Feasibility Study

TypeinterventionalSponsorUniversity of MilanRan2018 to 2020Enrolled60ConditionsGingival Recession, Palate, WoundArmsDGG Harvesting approach, ET harvesting approach, TDT harvesting approach, MT harvesting approach, Root coverage procedure
NCT06116539 phase1unknown statusnot on this mapstarted 2024, after this paper: background citation

Multicenter Randomized Clinical Trial of the Use of Cyanoacrylate in Healing and Pain in the Palatal Donor Site of Connective Tissue Grafts

TypeinterventionalSponsorAlfonso X El Sabio UniversityRan2024 to 2024Enrolled80ConditionsPain, Postoperative, Healing Surgical WoundsArmsCyanoacrylate, Suture
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 10 syntheses or guidelines pooled it, 92 citations in OpenAlex.

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  16. Cyanoacrylate Adhesive in Free Gingival Graft Healing: A Digital and Microcirculatory Randomized Clinical Trial.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Lorenzo TavelliDepartment of Periodontics & Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0003-4864-3964
Andrea RavidàDepartment of Periodontics & Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Muhammad H A SalehDepartment of Periodontics & Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Bartosz MaskaDepartment of Periodontics & Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
Fernando Suárez-López Del AmoDepartment of Periodontics, University of Oklahoma Health Sciences Center - College of Dentistry, Oklahoma City, OK, USA. fsuarezla@gmail.com.
Giulio RasperiniDepartment of Biomedical, Surgical and Dental Sciences, Foundation IRCCS Ca' Granda Polyclinic, University of Milan, Milan, Italy.
Hom-Lay WangDepartment of Periodontics & Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
University of Michigan · USUniversity of Milan · ITUniversity of Oklahoma Health Sciences Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to compare the effects of a hemostatic collagen sponge and a collagen sponge sealed with a bio-adhesive material on the palatal donor sites with the purpose of minimizing postoperative pain after epithelialized gingival graft (EGG) harvesting. MATERIAL AND

methodsThe present study consisted of 44 EGGs harvested in 44 patients. In the control group, a hemostatic collagen sponge was applied over the palatal wound, while the test group was treated with additional cyanoacrylate. Patients were observed for 14 days, evaluating the pain level by using the visual analogic scale. The consumption of analgesic during the postoperative period, the willingness for retreatment and the characteristic of the graft were also analyzed.

resultsStatistically significant differences in pain perception were found between test and control groups in each of the studied days (p < 0.01). Analgesic consumption was lower in the test group (p < 0.01). Graft width < 14 mm was found to be associated with lower discomfort (p < 0.01).

conclusionsAdding an additional layer of cyanoacrylate over a hemostatic collagen sponge on the palatal wound following EGG harvesting was found to be successful in minimizing the postoperative discomfort and the need for analgesics. CLINICAL RELEVANCE: Postoperative pain after palatal tissue harvesting can be successfully minimized if the donor site open wound is protected with an external layer of cyanoacrylate over a collagen sponge.

Indexed as

BandagesPain PerceptionAdultAgedAnalgesicsCollagenFemaleGingivaHemostaticsHumansMaleMiddle AgedPain MeasurementPostoperative PainProspective StudiesTissue AdhesivesAnalgesicsCollagenHemostaticsTissue AdhesivesAutograftsFree soft tissue graftPain managementWound healing

Identifiers

PMID29713890
OpenAlexW2802253334

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.