Evidence map›Paper›PMID 29713871›Full record

ReviewCurrent HIV/AIDS reports2018

Continued Interest and Controversy: Vitamin D in HIV.

Evelyn Hsieh, Michael T Yin

Open access · greenAbstract readReview
In one paragraph

Review in Current HIV/AIDS reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Uptake of Vitamins DNutrients · 2021
    Article
  10. Possible role of vitamin D in Covid-19 infection in pediatric population.Journal of endocrinological investigation · 2021
    Review
  11. Article
  12. The Role of Physical Activity for the Management of Sarcopenia in People Living with HIV.International journal of environmental research and public health · 2020
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Evelyn HsiehSection of Rheumatology, Yale School of Medicine, 300 Cedar Street, TAC S-525, PO Box 208031, New Haven, CT, 06517, USA. evelyn.hsieh@yale.edu.
Michael T YinDivision of Infectious Diseases, Columbia University Medical Center, New York, NY, USA.
Columbia University Irving Medical Center · USYale University · US

Funding

HIV and the menopausal transition: effects on musculoskeletal healthR01AI095089 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI YIN, MICHAEL T · 2011 to 2015
$3.3M
Risk for Bone Loss Among Individuals with HIV in a Resource-Limited EnvironmentK01TW009995 · FIC · YALE UNIVERSITY · PI HSIEH, EVELYN · 2015 to 2019
$693k
FIC NIH HHS K01 TW009995NIAID NIH HHS R01 AI095089
6 · The paper itself

Abstract

purpose of reviewVitamin D (VitD) deficiency is highly prevalent among HIV-infected individuals. Given the overlapping risk for several chronic disease and immunomodulatory outcomes from both long-standing HIV and VitD deficiency, there is great interest in clarifying the clinical role of VitD for this population. RECENT

findingsRecent studies have expanded our knowledge regarding the epidemiology and mechanisms of VitD deficiency-associated outcomes in the setting of HIV. Clinical trials focusing on VitD supplementation have demonstrated a positive impact on bone mineral density in subgroups of HIV-infected individuals initiating ART or on suppressive ART regimens; however, significant heterogeneity exists between studies and data are less consistent with other clinical outcomes. Further research is needed to clarify uncertainly in several domains, including identifying patients at greatest risk for poor outcomes from VitD deficiency, standardizing definitions and measurement techniques, and better quantifying the benefits and risks of VitD supplementation across different demographic strata for skeletal and extra-skeletal outcomes.

Indexed as

Vitamin D DeficiencyAnti-HIV AgentsBone DensityDietary SupplementsFemaleHIVHIV InfectionsHumansMaleRiskTenofovirVitamin DAnti-HIV AgentsTenofovirVitamin DAntiretroviral therapyCardiovascular diseaseHIV/AIDSImmune functionMusculoskeletal healthVitamin DVitamin D supplementation

Identifiers

PMID29713871
PMCPMC6003869
OpenAlexW2801478954

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.