ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2018
First time description of early lead failure of the Linox Smart lead compared to other contemporary high-voltage leads.
Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Early Experience with the Biotronik Protego ICD Lead.Journal of clinical medicine · 2022Article
- Recurrent implantable cardioverter-defibrillator shocks due to automatic deactivation of a right ventricular lead noise discrimination algorithm.HeartRhythm case reports · 2022Article
- Subcutaneous and Transvenous ICDs: an Update on Contemporary Questions and Controversies.Current cardiology reports · 2022Review
- Subcutaneous implantable cardioverter-defibrillators: long-term results of the EFFORTLESS study.European heart journal · 2022Article
- Comparison of the performance of implantable cardioverter-defibrillator leads among manufacturers.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2020Article
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Authors and funding
7 authors.
Funding
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Abstract
purposeEarly lead failure has recently been reported in ICD patients with Linox SD leads. We aimed to compare the long-term performance of the following lead model Linox Smart SD with other contemporary high-voltage leads.
methodsAll patients receiving high-voltage leads at our center between November 2009 and May 2017 were retrospectively analyzed. Lead failure was defined as the occurrence of one or more of the following: non-physiological high-rate episodes, low- or high-voltage impedance anomalies, undersensing, or non-capture.
resultsIn total, 220 patients were included (Linox Smart SD, n = 113; contemporary lead, n = 107). During a median follow-up of 3.8 years (IQR 1.6-5.9 years), a total of 16 (14 in Linox Smart SD and 2 in contemporary group) lead failures occurred, mostly due to non-physiological high-rate sensing or impedance abnormalities. Lead failure incidence rates per 100 person-years were 2.9 (95% CI 1.7-4.9) and 0.6 (95% CI 0.1-2.3) for Linox Smart SD compared to contemporary leads respectively. Kaplan Meier estimates of 5-year lead failure rates were 14.0% (95% CI 8.1-23.6%) and 1.3% (95% CI 0.2-8.9%), respectively (log-rank p = 0.028). Implantation of a Linox Smart SD lead increased the risk of lead failure with a hazard ratio (HR) of 4.53 (95% CI 1.03-19.95, p = 0.046) and 4.44 (95% CI 1.00-19.77, p = 0.05) in uni- and multivariable Cox models.
conclusionsThe new Linox Smart SD lead model was associated with high failure rates and should be monitored closely to detect early signs of lead failure.
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