ArticlePsychopharmacology2018
An improved within-session self-adjusting delay discounting procedure for the study of choice impulsivity in rats.
Article in Psychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- The Evolutionary Theory of Behavior Dynamics Predicts Delay Discounting.Perspectives on behavior science · 2025Article
- Dynamically Adjusting Intertemporal Choice Task in Rodents.The European journal of neuroscience · 2025Article
- Human laboratory models of reward in substance use disorder.Pharmacology, biochemistry, and behavior · 2024Review
- Methylphenidate, but not citalopram, decreases impulsive choice in rats performing a temporal discounting task.Frontiers in psychiatry · 2024Article
- Poke And Delayed Drink Intertemporal Choice Task (POKE-ADDICT): An open-source behavioral apparatus for intertemporal choice testing in rodents.Animal models and experimental medicine · 2023Article
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Authors and funding
3 authors.
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Abstract
rationaleDelay-discounting procedures involving choice between small immediate rewards and large delayed rewards are used to study impulsivity in rodents. Improving existing procedures may provide new insights into the neurobiological mechanisms underlying decision-making processes.
objectivesTo develop a novel delay-discounting procedure that adjusts the delay value within individual sessions based on the rat's most recent choices.
methodsCompared to previously developed procedure, we required a more consistent demonstration of preference, five consecutive choices of the large or small reward, a criterion that is more likely to reflect deliberate choice by the animal, as opposed to two consecutive choices. In addition, delays were changed in steps of 5 s (rather than 1 s), because 5-s increments should be more easily discriminated and may produce a more distinct effect on choice. We characterized the procedure behaviorally by manipulating the duration of the session and the consecutive choice criterion, and we investigated the stability of the behavior upon interruption of training. We also characterized the procedure pharmacologically by investigating the effects of dopaminergic compounds.
resultsOur procedures allowed obtaining two complementary measures of delay discounting: (1) the percentage of choices of the delay option and (2) the mean adjusting delay, an index of the delay that animals choose more frequently. We found that our procedure rapidly establishes a baseline of choice behavior that remains stable over time and is highly sensitive to manipulations of the dopaminergic system.
conclusionsThis procedure may provide a useful tool for investigating the neurobiology of inter-temporal choice and decision-making.
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