ArticleEuropean radiology2018
Is it painful to be different? Sciatic nerve anatomical variants on MRI and their relationship to piriformis syndrome.
Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Anatomical variations of the sciatic nerve and its relationship to the pelvic bone: a systematic review.Surgical and radiologic anatomy : SRA · 2026Pooled it
- Anatomical variations of the sciatic nerve: a literature review on morphology and clinical implications.Anatomical science international · 2026Review
- Anatomical variation of the sciatic nerve division in the cadaver studies: a systematic review and meta-analysis.Anatomy & cell biology · 2026Review
- Article
- Piriformis Syndrome Is Often Overlooked as a Cause of Gluteal Pain and Sciatica: Diagnostic Challenges and the Role of Imaging-A Narrative Review.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2025Review
- Piriformis preservation in total hip arthroplasty: do we have a new concept? An update on anatomy, function and clinical outcomes.EFORT open reviews · 2025Article
- Importance of Sacrotuberous Ligament in Transgluteal Approach for Sciatic Nerve Entrapment in the Greater Sciatic Notch (Piriformis Syndrome).Journal of Korean Neurosurgical Society · 2024Article
- Looking beyond Piriformis Syndrome: Is It Really the Piriformis?Hip & pelvis · 2023Review
- Article
- Physiotherapy for Piriformis Syndrome Using Sciatic Nerve Mobilization and Piriformis Release.Cureus · 2022Review
- Piriformis Syndrome (Sciatic Nerve Entrapment) Associated With Type C Sciatic Nerve Variation: A Report of Two Cases and Literature Review.Korean journal of neurotrauma · 2022Article
- Visualizing Anatomic Variants of the Sciatic Nerve Using Diagnostic Ultrasound During Piriformis Muscle Injection: An Example of 4 Cases.Journal of chiropractic medicine · 2022Article
- Intrapelvic entrapment of sacral nerve roots by abnormal bundles of the piriformis muscle: description of an extra-spinal cause of sciatica and pudendal neuralgia.Journal of hip preservation surgery · 2021Article
- Anatomical analysis of the pelvis to identify any predisposing anatomical factors for ischiofemoral space pathology: a retrospective study.The British journal of radiology · 2020Article
- Ultrasound elastography findings in piriformis muscle syndrome.The Indian journal of radiology & imagingArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the purported relationship between sciatic nerve variant anatomy and piriformis syndrome.
methodsOver 49 months, 1039 consecutive noncontrast adult hip MRIs were completed for various clinical indications. Repeat and technically insufficient studies were excluded. Radiologists categorized sciatic nerve anatomy into Beaton and Anson anatomical types. Chart review using our institution's cohort search and navigation tool determined the prevalence of the explicit clinical diagnosis of piriformis syndrome (primary endpoint) and sciatica and buttock pain (secondary endpoints). A Z-test compared the prevalence of each diagnosis in the variant anatomy and normal groups.
resultsSeven hundred eighty-three studies were included, with sciatic nerve variants present in 150 hips (19.2%). None of the diagnoses had a statistically significant difference in prevalence between the variant and normal hip groups. Specifically, piriformis syndrome was present in 11.3% of variant hips compared with 9.0% of normal hips (p = 0.39).
conclusionsThere were no significant differences in the prevalence of piriformis syndrome, buttock pain, or sciatica between normal and variant sciatic nerve anatomy. This large-scale correlative radiologic study into the relationship between sciatic nerve variants and piriformis syndrome calls into question this purported relationship. KEY POINTS: • Large retrospective study relating variant sciatic nerve anatomy, present in 19.2% of hip MRIs, and piriformis syndrome • While sciatic nerve variant anatomy has previously been implicated in piriformis syndrome in small studies, no relationship was identified between sciatic nerve variants and piriformis syndrome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.