ArticleScience advances2016
Whole-genome sequence analysis shows that two endemic species of North American wolf are admixtures of the coyote and gray wolf.
Article in Science advances, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
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Who cites it
72 citing papers in PubMed.
- On the ancestry and evolution of the extinct dire wolf.Cell genomics · 2026Article
- Multiple introgression events from ghost Rüppell's fox mitochondrial lineages into red fox.Scientific reports · 2026Article
- Population genomics reveals an ancient origin of heartworms in canids.Communications biology · 2026Article
- From individuals to communities: How genomics is transforming biodiversity conservation.Genetics and molecular biology · 2026Article
- From few to many: How non-model organisms' genomics broadened our understanding of molecular evolution.Genetics and molecular biology · 2026Article
- Article
- Development of a Noninvasive Genotyping-In-Thousands (GTseq) Panel for Long-Term Conservation of Western Great Lakes Gray Wolves (Ecology and evolution · 2025Article
- Coyotes can do 'puppy dog eyes' too: comparing interspecific variation inRoyal Society open science · 2024Article
- Rapid molecular species identification of mammalian scat samples using nanopore adaptive sampling.Journal of mammalogy · 2024Article
- The value of hybrid genomes: Building two highly contiguous reference genome assemblies to advance Canis genomic studies.The Journal of heredity · 2024Article
- Conservation genomics of wolves: The global impact of RK Wayne's research.The Journal of heredity · 2024Review
- Species delimitation, discovery and conservation in a tiger beetle species complex despite discordant genetic data.Scientific reports · 2024Article
- White and other fur colourations and hybridization in golden jackals (Canis aureus) in the Carpathian basin.Scientific reports · 2023Article
- The extinct Sicilian wolf shows a complex history of isolation and admixture with ancient dogs.iScience · 2023Article
- Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture.Genome biology · 2023Article
- Conservation implications of elucidating the Korean wolf taxonomic ambiguity through whole-genome sequencing.Ecology and evolution · 2023Article
- Pervasive Introgression During Rapid Diversification of the European Mountain Genus Soldanella (L.) (Primulaceae).Systematic biology · 2023Article
- Comparative genomics reveals the hybrid origin of a macaque group.Science advances · 2023Article
- Review
- Tracing Eastern Wolf Origins From Whole-Genome Data in Context of Extensive Hybridization.Molecular biology and evolution · 2023Article
12 more citing papers are in PubMed but not listed here.
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9 authors.
Funding
Abstract
Protection of populations comprising admixed genomes is a challenge under the Endangered Species Act (ESA), which is regarded as the most powerful species protection legislation ever passed in the United States but lacks specific provisions for hybrids. The eastern wolf is a newly recognized wolf-like species that is highly admixed and inhabits the Great Lakes and eastern United States, a region previously thought to be included in the geographic range of only the gray wolf. The U.S. Fish and Wildlife Service has argued that the presence of the eastern wolf, rather than the gray wolf, in this area is grounds for removing ESA protection (delisting) from the gray wolf across its geographic range. In contrast, the red wolf from the southeastern United States was one of the first species protected under the ESA and was protected despite admixture with coyotes. We use whole-genome sequence data to demonstrate a lack of unique ancestry in eastern and red wolves that would not be expected if they represented long divergent North American lineages. These results suggest that arguments for delisting the gray wolf are not valid. Our findings demonstrate how a strict designation of a species under the ESA that does not consider admixture can threaten the protection of endangered entities. We argue for a more balanced approach that focuses on the ecological context of admixture and allows for evolutionary processes to potentially restore historical patterns of genetic variation.
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