Evidence map›Paper›PMID 29713532›Full record

ArticleArab journal of urology2018

Lifestyle causes of male infertility.

Damayanthi Durairajanayagam

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Arab journal of urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed, 7 pooled it
36.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

155 citing papers in PubMed, 7 syntheses or guidelines pooled it, 398 citations in OpenAlex.

  1. Pooled it
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  5. SARS-CoV-2 effects on sperm parameters: a meta-analysis study.Journal of assisted reproduction and genetics · 2022
    Pooled it
  6. Association between exposure to ambient air pollution and semen quality in adults: a meta-analysis.Environmental science and pollution research international · 2022
    Pooled it
  7. Pooled it
  8. Trial
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  13. The role of date palm pollen in women's health and fertility: A narrative review.International journal of reproductive biomedicine · 2026
    Review
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  15. Article
  16. Review
  17. Article
  18. Article
  19. Indirubin-3'-oxime as a dual-action agent: mitigating heat-induced male infertility inJournal of enzyme inhibition and medicinal chemistry · 2025
    Article
  20. Mechanisms underlying methamphetamine-induced disruption of testicular integrity.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review

95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Damayanthi DurairajanayagamDiscipline of Physiology, Faculty of Medicine, Sungai Buloh Campus, Universiti Teknologi MARA, Selangor, Malaysia.
Universiti Teknologi MARA · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the potential effects of lifestyle factors on male reproductive health. Evidence of a global decline in human sperm quality over recent decades has been accumulating. Environmental, occupational, and modifiable lifestyle factors may contribute to this decline. This review focuses on key lifestyle factors that are associated with male infertility such as smoking cigarettes, alcohol intake, use of illicit drugs, obesity, psychological stress, advanced paternal age, dietary practices, and coffee consumption. Other factors such as testicular heat stress, intense cycling training, lack of sleep and exposure to electromagnetic radiation from mobile phone use are briefly discussed. MATERIALS AND

methodA comprehensive literature search was performed to identify and synthesise all relevant information, mainly from within the last decade, on the major lifestyle factors associated with male infertility and semen quality. Database searches were limited to reports published in English only. A manual search of bibliographies of the reports retrieved was conducted to identify additional relevant articles.

resultsIn all, 1012 articles were identified from the database search and after reviewing the titles and abstract of the reports, 104 articles met the inclusion criteria. Of these, 30 reports were excluded as the full-text could not be retrieved and the abstract did not have relevant data. The remaining 74 reports were reviewed for data on association between a particular lifestyle factor and male infertility and were included in the present review.

conclusionThe major lifestyle factors discussed in the present review are amongst the multiple potential risk factors that could impair male fertility. However, their negative impact may well be mostly overcome by behaviour modification and better lifestyle choices. Greater awareness and recognition of the possible impact of these lifestyle factors are important amongst couples seeking conception.

Indexed as

AAS, anabolic–androgenic steroidsAPA, advanced paternal ageART, assisted reproductive technologyASIH, anabolic steroid-induced hypogonadismBMI, body mass indexChk1, checkpoint kinase 1ECS, endogenous cannabinoid systemGnIH, gonadotropin-inhibitory hormoneHADS, Hospital Anxiety and Depression ScoreHPA, hypothalamus–pituitary–adrenalHPG, hypothalamus–pituitary–gonadalICSI, intracytoplasmic sperm injectionIUI, intrauterine inseminationIVF, in vitro fertilisationLifestyleMale infertilityMMP, mitochondrial membrane potentialRisk factorsROS, reactive oxygen speciesSemen qualitySOD, superoxide dismutaseSperm DNA fragmentation

Identifiers

PMID29713532
PMCPMC5922227
OpenAlexW2794132935

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.