ArticleOpen heart
Impact of periodontitis as representative of chronic inflammation on long-term clinical outcomes in patients with atrial fibrillation.
Article in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Association of periodontal disease with risk atrial fibrillation: systematic review.BMC oral health · 2025Pooled it
- Effects of Oral Inflammatory Diseases and Oral Hygiene on Atrial Fibrillation: A Systematic Review.International journal of clinical practice · 2023Pooled it
- Relationship between periodontitis and atrial fibrillation recurrence after ablation: a systematic review.Frontiers in cardiovascular medicine · 2026Review
- The Pathophysiology of Sex Differences in Stroke Risk and Prevention in Atrial Fibrillation: A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2025Review
- Cross-Sectional Study Demonstrating Specificity of Iron Kinetics in Atrial Fibrillation.Circulation reports · 2025Article
- Periodontitis impacts on thrombotic diseases: from clinical aspect to future therapeutic approaches.International journal of oral science · 2024Review
- Periodontal Treatment During the Blanking Period Improves the Outcome of Atrial Fibrillation Ablation.Journal of the American Heart Association · 2024Article
- Periodontal disease and risk of atrial fibrillation or atrial flutter: A systematic review and meta-analysis.Journal of arrhythmia · 2023Article
- Associations between Plasma Antibody Levels against Porphyromonas gingivalis and Atrial Fibrillation among Community-Dwelling Older Individuals in Japan: A Cross-Sectional Study.Oral health & preventive dentistry · 2023Article
- Article
- Periodontitis was associated with worse clinical outcomes after catheter ablation for paroxysmal atrial fibrillation.Frontiers in cardiovascular medicine · 2022Article
- Porphyromonas gingivalis and left atrial appendage spontaneous echo contrast in atrial fibrillation ablation candidates.Heart and vessels · 2021Article
- Role of Periodontal Infection, Inflammation and Immunity in Atherosclerosis.Current problems in cardiology · 2021Review
- Periodontal Inflammation and Systemic Diseases: An Overview.Frontiers in physiology · 2021Review
- Periodontitis, dental plaque, and atrial fibrillation in the Hamburg City Health Study.PloS one · 2021Article
- Quasi-Randomized Trial of Effects of Perioperative Oral Hygiene Instruction on Inpatients with Heart Diseases Using a Behavioral Six-Step Method.International journal of environmental research and public health · 2019Article
- Potential Impact of Oral Inflammations on Cardiac Functions and Atrial Fibrillation.Biomolecules · 2018Review
- Pericardial Effusion in Association With Periodontitis: Case Report and Review of 8 Patients in Literature.Journal of investigative medicine high impact case reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Relationship between atrial fibrillation (AF) and inflammation was shown in previous studies. However, there was limited data about the association between the periodontitis and AF in the long-term follow-up. The aim of this study was to evaluate the impact of periodontitis on long-term clinical outcomes in patients with AF. Methods: The Kosin University echocardiography, ECG and periodontitis database were reviewed from 2013 to 2015 to identify patients with AF. Those patients were divided into two groups according to the presence of periodontitis and clinical events including any arrhythmic attack, thromboembolic and bleeding and death were collected during a median of 18 months. Results: Among 227 patients with AF, 47 (20.7%) patients had periodontitis. Major adverse cardiac events (MACE) were significantly higher in patients with periodontitis compared with those without periodontitis (p<0.001). Arrhythmias including AF, atrial tachycardia, atrial premature beat, ventricular tachycardia and ventricular premature beat also occurred in 44 (93.6%) patients, which was higher significantly higher incidence in patients with periodontitis than in those without periodontitis (p<0.001). In univariate analysis, age, CHA Conclusions: The periodontitis as representative of chronic inflammation was an independent predictor of arrhythmic events and MACE in patients with AF.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.