Evidence map›Paper›PMID 29713392›Full record

ArticleClinical epigenetics2018

Fetal growth is associated with CpG methylation in the P2 promoter of the IGF1 gene.

Catherine Le Stunff, Anne-Laure Castell, Nicolas Todd, Clémence Mille, Marie-Pierre Belot, Nathalie Frament, Sylvie Brailly-Tabard, Alexandra Benachi, Delphine Fradin, Pierre Bougnères

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical epigenetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Catherine Le Stunff1Institut National de la Santé et de la Recherche Médicale U1169, Bicêtre Hospital, Paris Sud University, Le Kremlin-Bicêtre, France.ORCID 0000-0001-8419-0451
Anne-Laure Castell2Service de Médecine des Adolescents, Bicêtre Hospital, Paris Sud University, Le Kremlin-Bicêtre, France.
Nicolas Todd1Institut National de la Santé et de la Recherche Médicale U1169, Bicêtre Hospital, Paris Sud University, Le Kremlin-Bicêtre, France.
Clémence Mille1Institut National de la Santé et de la Recherche Médicale U1169, Bicêtre Hospital, Paris Sud University, Le Kremlin-Bicêtre, France.
Marie-Pierre Belot1Institut National de la Santé et de la Recherche Médicale U1169, Bicêtre Hospital, Paris Sud University, Le Kremlin-Bicêtre, France.
Nathalie Frament1Institut National de la Santé et de la Recherche Médicale U1169, Bicêtre Hospital, Paris Sud University, Le Kremlin-Bicêtre, France.
Sylvie Brailly-Tabard3Service de BiologieMoléculaire et Hormonologie, Bicêtre Hospital, Paris Sud University, Le Kremlin-Bicêtre, France.
Alexandra Benachi4Service de Gynécologie-Obstétrique, Antoine Béclère Hospital, Paris Sud University, Clamart, France.
Delphine Fradin5CRCINA, INSERM U1232, Université de Nantes, Nantes, France.
Pierre Bougnères1Institut National de la Santé et de la Recherche Médicale U1169, Bicêtre Hospital, Paris Sud University, Le Kremlin-Bicêtre, France.
Université Paris-Sud · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There are many reasons to think that epigenetics is a key determinant of fetal growth variability across the normal population. Since Methods: Cord blood was sampled in 159 newborns born to mothers prospectively followed during their pregnancy. A 142-item questionnaire was filled by mothers at inclusion, during the last trimester of the pregnancy and at the delivery. The methylation of selected CpGs located in the promoters of the Results: Methylation at Conclusion: The current results suggest that the methylation of

Indexed as

DNA MethylationAdultCpG IslandsEpigenesis, GeneticFemaleFetal BloodFetal DevelopmentGenetic Association StudiesHumansInfant, NewbornInsulin-Like Growth Factor IMaleMaternal AgePregnancyPregnancy Trimester, ThirdPromoter Regions, GeneticIGF1 protein, humanInsulin-Like Growth Factor IDNA methylationEpigeneticsGrowthNewborn

Identifiers

PMID29713392
PMCPMC5909239
OpenAlexW2799695733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.