Evidence map›Paper›PMID 29713353›Full record

ArticleCellular & molecular biology letters2018

The norpurpureine alkaloid from

Gabriela Sánchez, Omar Estrada, Giovana Acha, Alfonso Cardozo, Franshelle Peña, Marie Christine Ruiz, Fabián Michelangeli, Claudia Alvarado-Castillo

Open access · goldAbstract read
In one paragraph

Article in Cellular & molecular biology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Gabriela Sánchez1Centro de Biofísica y Bioquímica (CBB), Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, Bolivarian Republic of Venezuela.
Omar Estrada1Centro de Biofísica y Bioquímica (CBB), Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, Bolivarian Republic of Venezuela.
Giovana Acha1Centro de Biofísica y Bioquímica (CBB), Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, Bolivarian Republic of Venezuela.
Alfonso Cardozo2Laboratorio de Botánica Sistemática, Facultad de Agronomía, Universidad Central de Venezuela (UCV), Maracay, Bolivarian Republic of Venezuela.
Franshelle Peña1Centro de Biofísica y Bioquímica (CBB), Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, Bolivarian Republic of Venezuela.
Marie Christine Ruiz1Centro de Biofísica y Bioquímica (CBB), Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, Bolivarian Republic of Venezuela.
Fabián Michelangeli1Centro de Biofísica y Bioquímica (CBB), Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, Bolivarian Republic of Venezuela.
Claudia Alvarado-Castillo1Centro de Biofísica y Bioquímica (CBB), Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, Bolivarian Republic of Venezuela.ORCID 0000-0002-1352-2524
Instituto Venezolano de Investigaciones Científicas · VECentral University of Venezuela · VE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe leaves of

methodsThe compounds in an

resultsThe benzylisoquinoline alkaloid norpurpureine was identified as the major anti-platelet compound. The IC

conclusionNorpurpureine displays a promising in vitro pharmacological profile as an inhibitor of human platelet activation. Its molecular target could be a common effector between Ca

Indexed as

Adenosine DiphosphateAlkaloidsAnimalsAnnonaBenzylisoquinolinesBlood PlateletsHumansInhibitory Concentration 50Molecular StructurePlant ExtractsPlant LeavesPlatelet AdhesivenessPlatelet AggregationPlatelet Aggregation InhibitorsPrimary Cell CultureRabbitsAdenosine DiphosphateAlkaloidsBenzylisoquinolinesnorpurpureinePlant ExtractsPlatelet Aggregation InhibitorsAlkaloidsAnnona purpureaHuman plateletsNorpurpureine

Identifiers

PMID29713353
PMCPMC5905151
OpenAlexW2799878868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.