Evidence map›Paper›PMID 29713314›Full record

ArticleFrontiers in microbiology2018

Background Adjusted Alignment-Free Dissimilarity Measures Improve the Detection of Horizontal Gene Transfer.

Kujin Tang, Yang Young Lu, Fengzhu Sun

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The statistical power ofSynthetic and systems biotechnology · 2019
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Kujin TangMolecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles, CA, United States.
Yang Young LuMolecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles, CA, United States.
Fengzhu SunMolecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles, CA, United States.
University of Southern California · USFudan University · CN

Funding

Computational Studies of Virus-host Interactions Using Metagenomics Data and ApplicationsR01GM120624 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AHLGREN, NATHAN, SUN, FENGZHU · 2017 to 2020
$1.7M
NIGMS NIH HHS R01 GM120624
6 · The paper itself

Abstract

Horizontal gene transfer (HGT) plays an important role in the evolution of microbial organisms including bacteria. Alignment-free methods based on single genome compositional information have been used to detect HGT. Currently, Manhattan and Euclidean distances based on tetranucleotide frequencies are the most commonly used alignment-free dissimilarity measures to detect HGT. By testing on simulated bacterial sequences and real data sets with known horizontal transferred genomic regions, we found that more advanced alignment-free dissimilarity measures such as

Indexed as

alignment-freeCVTreed*2genomic islandhorizontal gene transferkmer

Identifiers

PMID29713314
PMCPMC5911508
OpenAlexW2799437413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.