Evidence map›Paper›PMID 29713261›Full record

ArticleFrontiers in neuroscience2018

Transcranial Direct Current Stimulation (tDCS) Can Modulate EEG Complexity of Children With Autism Spectrum Disorder.

Jiannan Kang, Erjuan Cai, Junxia Han, Zhen Tong, Xin Li, Estate M Sokhadze, Manuel F Casanova, Gaoxiang Ouyang, Xiaoli Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  6. Trial
  7. Multisession tDCS combined with intrastimulation training improves emotion recognition in adolescents with autism spectrum disorder.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
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  16. Brain Complexity and Psychiatric Disorders.Iranian journal of psychiatry · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiannan KangInstitute of Electrical Engineering, Yanshan University, Qinhuangdao, China.
Erjuan CaiInstitute of Biomedical Engineering, Yanshan University, Qinhuangdao, China.
Junxia HanState Key Laboratory of Cognitive Neuroscience and Learning, IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Zhen TongInstitute of Electrical Engineering, Yanshan University, Qinhuangdao, China.
Xin LiInstitute of Biomedical Engineering, Yanshan University, Qinhuangdao, China.
Estate M SokhadzeDepartment of Biomedical Sciences, School of Medicine Greenville Campus, Greenville Health System, University of South Carolina, Greenville, SC, United States.
Manuel F CasanovaDepartment of Biomedical Sciences, School of Medicine Greenville Campus, Greenville Health System, University of South Carolina, Greenville, SC, United States.
Gaoxiang OuyangKey Laboratory of Measurement Technology and Instrumentation of Hebei Province, Qinhuangdao, China.
Xiaoli LiState Key Laboratory of Cognitive Neuroscience and Learning, IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder which affects the developmental trajectory in several behavioral domains, including impairments of social communication, cognitive and language abilities. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique, and it was used for modulating the brain disorders. In this paper, we enrolled 13 ASD children (11 males and 2 females; mean ± SD age: 6.5 ± 1.7 years) to participate in our trial. Each patient received 10 treatments over the dorsolateral prefrontal cortex (DLPFC) once every 2 days. Also, we enrolled 13 ASD children (11 males and 2 females; mean ± SD age: 6.3 ± 1.7 years) waiting to receive therapy as controls. A maximum entropy ratio (MER) method was adapted to measure the change of complexity of EEG series. It was found that the MER value significantly increased after tDCS. This study suggests that tDCS may be a helpful tool for the rehabilitation of children with ASD.

Indexed as

autism spectrum disorder (ASD)complexityelectroencephalography (EEG)maximum entropy ratio (MER)transcranial direct current stimulation (tDCS)

Identifiers

PMID29713261
PMCPMC5911939

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.