Evidence map›Paper›PMID 29713250›Full record

Trial reportJournal of the International Society of Sports Nutrition2018

Effects of β-alanine supplementation during a 5-week strength training program: a randomized, controlled study.

José Luis Maté-Muñoz, Juan H Lougedo, Manuel V Garnacho-Castaño, Pablo Veiga-Herreros, María Del Carmen Lozano-Estevan, Pablo García-Fernández, Fernando de Jesús, Jesús Guodemar-Pérez, Alejandro F San Juan, Raúl Domínguez

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05096793 (Acute Supplementation With Beta-Alanine Improves Performance in Aerobic-anaerobic Transition Zones in Endurance Athletes), which is not on this map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05096793 nacompletednot on this mapstarted 2021, after this paper: background citation

Acute Supplementation With Beta-Alanine Improves Performance in Aerobic-anaerobic Transition Zones in Endurance Athletes

TypeinterventionalSponsorUniversity of AmericasRan2021 to 2021Enrolled12ConditionsBeta-alanineArmsbeta alanine
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

José Luis Maté-Muñoz1Department of Physical Activity and Sport Sciences, Faculty of Health Sciences, Alfonso X El Sabio University, Avda, Universidad 1, Building C, 3rd floor, Office C-A15, Villanueva de la Cañada, 28691 Madrid, Spain.
Juan H Lougedo1Department of Physical Activity and Sport Sciences, Faculty of Health Sciences, Alfonso X El Sabio University, Avda, Universidad 1, Building C, 3rd floor, Office C-A15, Villanueva de la Cañada, 28691 Madrid, Spain.
Manuel V Garnacho-Castaño2Department of Physical Activity and Sport Sciences, TecnoCampus, College of Health Sciences, Pompeu Fabra University, Ernest Lluch, 32 (Porta Laietana), 08302 Mataró-Barcelona, Spain.
Pablo Veiga-Herreros3Department of Pharmacy, Faculty of Health Sciences, Alfonso X El Sabio University, Avda, Universidad 1, Building C, 3rd floor, Office C-A04, Villanueva de la Cañada, 28691 Madrid, Spain.
María Del Carmen Lozano-Estevan4Department of Pharmacy, Faculty of Health Sciences, Alfonso X El Sabio University, Avda, Universidad 1, Building D, 3rd floor, Office D-342, Villanueva de la Cañada, 28691 Madrid, Spain.
Pablo García-Fernández5Department of Physiotherapy, Faculty of Health Sciences, Alfonso X El Sabio University, Avda, Universidad, 1, Building C, 3rd floor, Office C-H05, Villanueva de la Cañada, 28691 Madrid, Spain.
Fernando de Jesús6Department of Pharmacy, Faculty of Health Sciences, Alfonso X El Sabio University, Avda, Universidad 1, Building D, 3rd floor, Office D-348, Villanueva de la Cañada, 28691 Madrid, Spain.
Jesús Guodemar-Pérez7Department of Physiotherapy, Faculty of Health Sciences, Camilo José Cela University, Urb, Villafranca del Castillo, Calle Castillo de Alarcón, 49, Villanueva de la Cañada, 28692 Madrid, Spain.
Alejandro F San JuanDepartment of Health and Human Performance. Faculty of Physical Activity and Sport Sciences, Polytechnic University, Social Building, 2nd floor, Office 205, Madrid, Spain.
Raúl Domínguez9Department of Physical Activity and Sport Sciences, Faculty of Health Sciences, Alfonso X El Sabio University, Avda, Universidad 1, Building C, 3rd floor, Office C-A12, Villanueva de la Cañada, 28691 Madrid, Spain.
Universidad Alfonso X el Sabio · ESCamilo José Cela University · ESPompeu Fabra University · ESYahoo (Spain) · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundβ-Alanine (BA) is a non-essential amino acid that has been shown to enhance exercise performance. The purpose of this investigation was to determine if BA supplementation improved the adaptive response to five weeks of a resistance training program.

methodsThirty healthy, strength-trained individuals were randomly assigned to the experimental groups placebo (PLA) or BA. Over 5 weeks of strength training, subjects in BA took 6.4 g/day of BA as 8 × 800 mg doses each at least 1.5 h apart. The training program consisted of 3 sessions per week in which three different leg exercises were conducted as a circuit (back squat, barbell step ups and loaded jumping lunges). The program started with 3 sets of 40 s of work per exercise and rest periods between sets of 120 s in the first week. This training volume was then gradually built up to 5 sets of 20 s work/60 s rest in the fifth week. The work load during the program was set by one of the authors according to the individual's perceived effort the previous week. The variables measured were average velocity, peak velocity, average power, peak power, and load in kg in a back squat, incremental load, one-repetition maximum (1RM) test. In addition, during the rest period, jump ability (jump height and power) was assessed on a force platform. To compare data, a general linear model with repeated measures two-way analysis of variance was used.

resultsSignificantly greater training improvements were observed in the BA group versus PLA group (

conclusionsβ-Alanine supplementation was effective at increasing power output when lifting loads equivalent to the individual's maximal strength or when working at maximum power output. The improvement observed at 1RM was explained by a greater load lifted, or strength gain, in response to training in the participants who took this supplement.

Indexed as

Dietary SupplementsResistance TrainingAdolescentAdultbeta-AlanineExercise TestHumansMaleMuscle, SkeletalMuscle StrengthSports Nutritional Physiological PhenomenaYoung Adultbeta-AlanineAverage powerExercise programJump heightOne-repetition maximum testβ-alanine

Identifiers

PMID29713250
PMCPMC5918575
OpenAlexW2802703456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.