ArticleInternational journal of chronic obstructive pulmonary disease
Heterogeneity of asthma and COPD overlap.
Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Asthma and chronic obstructive disease overlap (ACO), a systematic review of prevalence and co-morbidity factors based on diagnostic criteria.Journal of pharmaceutical policy and practice · 2026Review
- Spatial phenotyping of human bronchial airways in obstructive lung disease.Respiratory research · 2025Article
- Clinical characteristics of asthma-chronic obstructive pulmonary disease overlap phenotypes.Postepy dermatologii i alergologii · 2025Article
- Clinical implications of wheezing in patients with chronic obstructive pulmonary disease.Journal of thoracic disease · 2023Article
- Characteristics and difference of respiratory diseases in Korean adults aged ≥40 years: A cross-sectional study.The clinical respiratory journal · 2023Article
- Phenotype of Asthma-COPD Overlap in COPD and Severe Asthma Cohorts.Journal of Korean medical science · 2022Article
- Status of Studies Investigating Asthma-Chronic Obstructive Pulmonary Disease Overlap in Korea: A Review.Tuberculosis and respiratory diseases · 2022Review
- Editorial: The heterogeneity in COPD phenotypes.Frontiers in medicine · 2022Article
- ACO: Time to move from the description of different phenotypes to the treatable traits.PloS one · 2019Article
- Clinical, laboratory, and functional characteristics of asthma-COPD overlap in patients with a primary diagnosis of COPD.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e TisilogiaArticle
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Authors and funding
10 authors.
Funding
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Abstract
backgroundAsthma and COPD are heterogeneous diseases. Patients with both disease features (asthma-COPD overlap [ACO]) are common. However, clinical characteristics and socio-economic burden of ACO are still controversial. The aim of this study was to identify the heterogeneity of ACO and to find out the subtypes with clinical impact among ACO subtypes.
methodsIn the Korean National Health and Nutrition Examination Survey (KNHANES) conducted between 2007 and 2012, subjects who were ≥40 years and had prebronchodilator FEV
resultsThe asthma-predominant ACO group showed the lowest socioeconomic status, FEV
conclusionAsthma-predominant ACO individuals displayed poorer socioeconomic status and QoL compared to the COPD-predominant ACO group. The COPD-predominant ACO group displayed more frequent exacerbations and greater medical costs. Considering the heterogeneity of ACO, it is desirable to identify subtypes of ACO patients and appropriately allocate limited medical resources.
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