ArticleNature chemistry2018
Rapid phenolic O-glycosylation of small molecules and complex unprotected peptides in aqueous solvent.
Article in Nature chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 141 citations in OpenAlex.
- A Protecting-Group-Free S‑Glycosylation Strategy for Complex S‑Glycopeptide Synthesis.JACS Au · 2026Article
- StereoselectiveJACS Au · 2026Article
- Catalyst-Controlled Chemoselective β-Mannosylation of Phenols Via Attractive Noncovalent Interactions.Journal of the American Chemical Society · 2026Article
- Collision-free morgan fingerprints: a principled approach to enhance machine learning performance and interpretability in chemistry.Journal of cheminformatics · 2026Article
- Synthesis and Structural Confirmation of Secalosides A and B.Journal of the American Chemical Society · 2026Article
- Combinatorial QM and MD in silico design of natural product-based DHFR inhibitors.Scientific reports · 2025Article
- Protective Effects ofAntioxidants (Basel, Switzerland) · 2025Article
- Enantiomeric diarylheptanoids from Ottelia acuminata var. acuminata and their α-glucosidase inhibitory activity.Natural products and bioprospecting · 2025Article
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- Cooperative Catalysis in StereoselectiveJournal of the American Chemical Society · 2024Article
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- Unconventional posttranslational modification in innate immunity.Cellular and molecular life sciences : CMLS · 2024Review
- Anion-Bridged Dual Hydrogen Bond Enabled Concerted Addition of Phenol to Glycal.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Unraveling the promoter effect and the roles of counterion exchange in glycosylation reaction.Science advances · 2023Article
- C-H Glycosylation of Native Carboxylic Acids: Discovery of Antidiabetic SGLT-2 Inhibitors.ACS central science · 2023Article
- Parallel pathways for serotonin biosynthesis and metabolism in C. elegans.Nature chemical biology · 2023Article
- Tyrosine bioconjugation with hypervalent iodine.Chemical science · 2022Article
- Site-Selective Modification of (Oligo)Saccharides.ACS catalysis · 2022Review
- Chemistry and Bioactivity ofMolecules (Basel, Switzerland) · 2022Article
- Synthesis and Glycosidation of Anomeric Halides: Evolution from Early Studies to Modern Methods of the 21st Century.Chemical reviews · 2022Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Glycosylated natural products and synthetic glycopeptides represent a significant and growing source of biochemical probes and therapeutic agents. However, methods that enable the aqueous glycosylation of endogenous amino acid functionality in peptides without the use of protecting groups are scarce. Here, we report a transformation that facilitates the efficient aqueous O-glycosylation of phenolic functionality in a wide range of small molecules, unprotected tyrosine, and tyrosine residues embedded within a range of complex, fully unprotected peptides. The transformation, which uses glycosyl fluoride donors and is promoted by Ca(OH)
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.