ArticleNature chemistry2018
Amino-acid-encoded biocatalytic self-assembly enables the formation of transient conducting nanostructures.
Article in Nature chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed.
- Pathway Controlled Phase Separation of Minimal Building Blocks Utilizing a Dissociative Chemical Transformation.Angewandte Chemie (International ed. in English) · 2026Article
- Electrochemically Triggered Supramolecular Polymerization Under Kinetic Control.Angewandte Chemie (International ed. in English) · 2026Article
- Bridging stimulus-responsive and dissipative peptide assemblies to build complex interactive biomaterials.Nature reviews. Chemistry · 2026Review
- Light and Dark Cycles Control the Structural Evolution of Photoresponsive Supramolecular Systems.Angewandte Chemie (International ed. in English) · 2026Article
- Selective binding of sulphated glycosaminoglycans induces self-assembly of naphthalene diimide into fluorescent nanofibers.Nanoscale · 2026Article
- Regulating Promiscuous Catalysis via Substrate-Induced Transient Assembly.Angewandte Chemie (International ed. in English) · 2026Article
- FunctionalACS bio & med chem Au · 2025Article
- Chirality Makes or Breaks Chemically Driven Self-Assembly.Angewandte Chemie (International ed. in English) · 2025Article
- A family of tubular pili from harmful algal bloom forming cyanobacterium Microcystis aeruginosa.Nature communications · 2025Article
- Self-Regulating Hydrogel with Reversible Optical Activity in Its Gel-to-Gel Transformation.Journal of the American Chemical Society · 2025Article
- Unraveling the Atomistic Mechanism of Electrostatic Lateral Association of Peptide β-Sheet Structures and Its Role in Nanofiber Growth and Hydrogelation.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Molecular-scale dissipative chemistry drives the formation of nanoscale assemblies and their macroscale transport.Nature chemistry · 2025Article
- Short Peptide and Amino Acid-Based Supramolecular Ionogels and Eutectogels.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024Review
- Semi-crystalline polymers with supramolecular synergistic interactions: from mechanical toughening to dynamic smart materials.Chemical science · 2024Review
- Using a biocatalyzed reaction cycle for transient and pH-dependent host-guest supramolecular hydrogels.Journal of materials chemistry. B · 2024Article
- Biomimetic chiral hydrogen-bonded organic-inorganic frameworks.Nature communications · 2024Article
- Therapeutic Supramolecular Polymers: Designs and Applications.Progress in polymer science · 2024Article
- Transient co-assemblies of micron-scale colloids regulated by ATP-fueled reaction networks.Chemical science · 2023Article
- Programmable supramolecular chirality in non-equilibrium systems affording a multistate chiroptical switch.Nature communications · 2023Article
- Mechanosensitive non-equilibrium supramolecular polymerization in closed chemical systems.Nature communications · 2023Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aqueous compatible supramolecular materials hold promise for applications in environmental remediation, energy harvesting and biomedicine. One remaining challenge is to actively select a target structure from a multitude of possible options, in response to chemical signals, while maintaining constant, physiological conditions. Here, we demonstrate the use of amino acids to actively decorate a self-assembling core molecule in situ, thereby controlling its amphiphilicity and consequent mode of assembly. The core molecule is the organic semiconductor naphthalene diimide, functionalized with D- and L- tyrosine methyl esters as competing reactive sites. In the presence of α-chymotrypsin and a selected encoding amino acid, kinetic competition between ester hydrolysis and amidation results in covalent or non-covalent amino acid incorporation, and variable supramolecular self-assembly pathways. Taking advantage of the semiconducting nature of the naphthalene diimide core, electronic wires could be formed and subsequently degraded, giving rise to temporally regulated electro-conductivity.
Indexed as
Identifiers
29713031What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.