Evidence map›Paper›PMID 29713015›Full record

ArticleNature immunology2018

Atherogenic dyslipidemia promotes autoimmune follicular helper T cell responses via IL-27.

Heeju Ryu, Hoyong Lim, Garam Choi, Young-Jun Park, Minkyoung Cho, Hyeongjin Na, Chul Won Ahn, Young Chul Kim, Wan-Uk Kim, Sang-Hak Lee and 1 more

Erratum issuedOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 84 citations in OpenAlex.

  1. Article
  2. ApoB-specific CD4Frontiers in immunology · 2026
    Review
  3. Recent Insights Into Targeting Interleukin-27 in Coronary Artery Disease.Journal of cardiovascular translational research · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Control of T-cell immunity by fatty acid metabolism.Annals of pediatric endocrinology & metabolism · 2024
    Article
  9. Review
  10. Review
  11. T-Cell/B-Cell Interactions in Atherosclerosis.Arteriosclerosis, thrombosis, and vascular biology · 2024
    Review
  12. Article
  13. FasClinical immunology (Orlando, Fla.) · 2024
    Article
  14. Review
  15. Review
  16. Review
  17. Liver X receptor controls follicular helper T cell differentiation via repression of TCF-1.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Article
  19. Review
  20. T cell help in the autoreactive germinal center.Scandinavian journal of immunology · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Heeju RyuLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
Hoyong LimLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
Garam ChoiLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
Young-Jun ParkLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
Minkyoung ChoLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
Hyeongjin NaLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea.
Chul Won AhnBK21 Plus program, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.
Young Chul KimBK21 Plus program, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.
Wan-Uk KimCenter for Integrative Rheumatoid Transcriptomics and Dynamics, The Catholic University of Korea, Seoul, Republic of Korea.
Sang-Hak LeeDivision of Cardiology, Department of Internal Medicine, Severance Hospital, College of Medicine, Yonsei University, Seoul, Republic of Korea.
Yeonseok ChungLaboratory of Immune Regulation, Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea. yeonseok@snu.ac.kr.ORCID http://orcid.org/0000-0001-5780-4841
Seoul National University · KRCatholic University of Korea · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of atherosclerosis is higher among patients with systemic lupus erythematosus (SLE); however, the mechanism by which an atherogenic environment affects autoimmunity remains unclear. We found that reconstitution of atherosclerosis-prone Apoe

Indexed as

AnimalsAtherosclerosisAutoimmunityCell DifferentiationDendritic CellsDyslipidemiasInterleukinsLupus Erythematosus, SystemicMiceMice, KnockoutT-Lymphocytes, Helper-InducerToll-Like Receptor 4Il27 protein, mouseInterleukinsTlr4 protein, mouseToll-Like Receptor 4

Identifiers

PMID29713015
OpenAlexW2802029623

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.