Evidence map›Paper›PMID 29712855›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

FACT complex is required for DNA demethylation at heterochromatin during reproduction in

Jennifer M Frost, M Yvonne Kim, Guen Tae Park, Ping-Hung Hsieh, Miyuki Nakamura, Samuel J H Lin, Hyunjin Yoo, Jaemyung Choi, Yoko Ikeda, Tetsu Kinoshita and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
10.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 73 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Facilitates Chromatin Transcription in Breast and Other Cancers.Advances in experimental medicine and biology · 2024
    Review
  12. Article
  13. Article
  14. Review
  15. DNA methylation dynamics during germline development.Journal of integrative plant biology · 2022
    Review
  16. Article
  17. Genome-Wide Analysis of theInternational journal of molecular sciences · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 5 countries.

Jennifer M FrostDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720.
M Yvonne KimDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720.
Guen Tae ParkDepartment of Biological Sciences, Seoul National University, 151-747 Seoul, Korea.
Ping-Hung HsiehDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720.
Miyuki NakamuraLinnean Center for Plant Biology, Department of Plant Biology, Swedish University of Agricultural Sciences, SE-75007 Uppsala, Sweden.
Samuel J H LinDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720.ORCID 0000-0002-4424-7086
Hyunjin YooDepartment of Biological Sciences, Seoul National University, 151-747 Seoul, Korea.
Jaemyung ChoiDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720.
Yoko IkedaInstitute of Plant Science and Resources, Okayama University, Kurashiki, 710-0046 Okayama, Japan.ORCID 0000-0002-3150-8902
Tetsu KinoshitaKihara Institute for Biological Research, Yokohama City University, Yokohama, 244-0813 Kanagawa, Japan; tkinoshi@yokohama-cu.ac.jp yhc@snu.ac.kr daniel.zilberman@jic.ac.uk rfischer@berkeley.edu.
Yeonhee ChoiDepartment of Biological Sciences, Seoul National University, 151-747 Seoul, Korea; tkinoshi@yokohama-cu.ac.jp yhc@snu.ac.kr daniel.zilberman@jic.ac.uk rfischer@berkeley.edu.
Daniel ZilbermanDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720; tkinoshi@yokohama-cu.ac.jp yhc@snu.ac.kr daniel.zilberman@jic.ac.uk rfischer@berkeley.edu.
Robert L FischerDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720; tkinoshi@yokohama-cu.ac.jp yhc@snu.ac.kr daniel.zilberman@jic.ac.uk rfischer@berkeley.edu.
University of California, Berkeley · USSeoul National University · KRJohn Innes Centre · GBKihara Institute for Biological Research · JPOkayama University · JPSwedish University of Agricultural Sciences · SE

Funding

Regulation and Function of DNA Demethylation in ArabidopsisR01GM069415 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI FISCHER, ROBERT L, ZILBERMAN, DANIEL · 2004 to 2016
$3.8M
Genome Sequencer FLXS10RR029668 · NCRR · UNIVERSITY OF CALIFORNIA BERKELEY · PI NGAI, JOHN J. · 2010 to 2010
$623k
Pacific Biosciences PacBio RS Single Molecule Real Time SequencerS10OD018174 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI ROKHSAR, DANIEL SOLEYMAN · 2014 to 2014
$600k
Illumina Sequencer to Facilitate Functional Genomics at BerkeleyS10RR027303 · NCRR · UNIVERSITY OF CALIFORNIA BERKELEY · PI TAYLOR, JOHN W. · 2010 to 2010
$500k
Biotechnology and Biological Sciences Research Council BBS/E/J/000PR9773NCRR NIH HHS S10 RR027303NCRR NIH HHS S10 RR029668NIGMS NIH HHS R01 GM069415NIH HHS S10 OD018174
6 · The paper itself

Abstract

The DEMETER (DME) DNA glycosylase catalyzes genome-wide DNA demethylation and is required for endosperm genomic imprinting and embryo viability. Targets of DME-mediated DNA demethylation reside in small, euchromatic, AT-rich transposons and at the boundaries of large transposons, but how DME interacts with these diverse chromatin states is unknown. The STRUCTURE SPECIFIC RECOGNITION PROTEIN 1 (SSRP1) subunit of the chromatin remodeler FACT (facilitates chromatin transactions), was previously shown to be involved in the DME-dependent regulation of genomic imprinting in

Indexed as

DNA DemethylationGene Expression Regulation, PlantGenomic ImprintingHeterochromatinArabidopsisArabidopsis ProteinsCell NucleusDNA, PlantEndospermOvulePlants, Genetically ModifiedPollenTranscription, GeneticArabidopsis ProteinsDNA, PlantHeterochromatinchromatinDEMETER demethylaseFACT complexgenomic imprintingreproduction

Identifiers

PMID29712855
PMCPMC5960277
OpenAlexW2950176439

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.