ArticleProceedings of the National Academy of Sciences of the United States of America2018
Catalytic amino acid production from biomass-derived intermediates.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 244 citations in OpenAlex.
- Performance comparison of downstream unit operations and process chains for the purification of amino acids for food, feed and pharma applications.Biotechnology reports (Amsterdam, Netherlands) · 2026Review
- Ru-enabled dehydration-reductive amination of α-, β-hydroxy acids into amino acids.Nature communications · 2026Article
- Optimal Design of Catalysts for Photoreforming Lactic Acid/Polylactic Acid to Clean Fuels and Value-Added Chemicals.ChemSusChem · 2026Review
- Research Progress on the Physiological Functions of Aspartic Acid and Its Applications in Animal Production.Animals : an open access journal from MDPI · 2026Review
- Oxide Layer Formation on AA2024-T3 Aircraft Alloy via Anodization in Environmentally Conscious Organic Acid Electrolytes.Materials (Basel, Switzerland) · 2026Article
- Selective Reductive Amination of Carbonyls to Primary Amines Under Ambient Conditions Over Rh/MFM-300(Cr).Angewandte Chemie (International ed. in English) · 2025Article
- Synthesis of aliphatic α-hydroxy carboxylic acidsRSC advances · 2025Article
- Rational Design of Advanced Functional Catalysts for Photo-Reforming Glucose into Bio-Derived Fuels and Chemicals.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Photocatalytic upcycling of polylactic acid to alanine by sulfur vacancy-rich cadmium sulfide.Nature communications · 2025Article
- Atomically dispersed cobalt catalysts for tandem synthesis of primary benzylamines from oxidized β-O-4 segments.Chemical science · 2024Article
- Selective production of methylindan and tetralin with xylose or hemicellulose.Nature communications · 2024Article
- Sustainable Soil Additives for Water and Micronutrient Supply: Swelling and Chelating Properties of Polyaspartic Acid Hydrogels Utilizing Newly Developed Crosslinkers.Gels (Basel, Switzerland) · 2024Article
- Highly Efficient Ru-Based Catalysts for Lactic Acid Conversion to Alanine.Nanomaterials (Basel, Switzerland) · 2024Article
- Synthesis of Polypeptides and Poly(α-hydroxy esters) from Aldehydes Using Strecker Synthesis.ACS omega · 2023Article
- Synthesis of piperidines and pyridine from furfural over a surface single-atom alloy RuNature communications · 2023Article
- Sustainable production of dopamine hydrochloride from softwood lignin.Nature communications · 2023Article
- Efficient conversion of lactic acid to alanine over noble metal supported on Ni@C catalysts.RSC advances · 2022Article
- Sustainable production of benzene from lignin.Nature communications · 2021Article
- Highly selective and robust single-atom catalyst RuNature communications · 2021Article
- Synthesis of bio-based methylcyclopentadiene via direct hydrodeoxygenation of 3-methylcyclopent-2-enone derived from cellulose.Nature communications · 2021Article
Corrections and comments
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Authors and funding
15 authors at 5 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amino acids are the building blocks for protein biosynthesis and find use in myriad industrial applications including in food for humans, in animal feed, and as precursors for bio-based plastics, among others. However, the development of efficient chemical methods to convert abundant and renewable feedstocks into amino acids has been largely unsuccessful to date. To that end, here we report a heterogeneous catalyst that directly transforms lignocellulosic biomass-derived α-hydroxyl acids into α-amino acids, including alanine, leucine, valine, aspartic acid, and phenylalanine in high yields. The reaction follows a dehydrogenation-reductive amination pathway, with dehydrogenation as the rate-determining step. Ruthenium nanoparticles supported on carbon nanotubes (Ru/CNT) exhibit exceptional efficiency compared with catalysts based on other metals, due to the unique, reversible enhancement effect of NH
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.