ArticleGenome research2018
A comparative transcriptional landscape of maize and sorghum obtained by single-molecule sequencing.
Article in Genome research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.
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Who cites it
57 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Perennials as Future Grain Crops: Opportunities and Challenges.Frontiers in plant science · 2022Pooled it
- Genome-wide association and haplotype analyses reveal genetic architecture of seed dormancy in grain sorghum with implications for preharvest sprouting tolerance.The plant genome · 2026Article
- A pangenome of maize provides genetic insights into drought resistance.Nature genetics · 2025Article
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- Homeostasis of glucose and lipid metabolism during physiological responses to a simulated hypoxic high altitude environment.Nature communications · 2025Article
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- Up-Frameshift Factors from Phytopathogenic Fungi Play a Crucial Role in Nonsense-Mediated mRNA Decay.Journal of fungi (Basel, Switzerland) · 2025Article
- Widespread impact of transposable elements on the evolution of post-transcriptional regulation in the cotton genus Gossypium.Genome biology · 2025Article
- High-quality chromosome scale genome assemblies of two important Sorghum inbred lines, Tx2783 and RTx436.NAR genomics and bioinformatics · 2024Article
- Transcriptome and metabolome analyses reveal regulatory networks associated with nutrition synthesis in sorghum seeds.Communications biology · 2024Article
- Genome-Wide Identification of Sorghum Paclobutrazol-Resistance Gene Family and Functional Characterization ofInternational journal of molecular sciences · 2024Article
- Genetic diversity, population structure, and a genome-wide association study of sorghum lines assembled for breeding in Uganda.Frontiers in plant science · 2024Article
- Full-length single-molecule sequencing uncovers novel insight into the global landscape of the cold stress response in trifoliate orange (Frontiers in plant science · 2024Article
- Characterization of the SWI/SNF complex and nucleosome organization in sorghum.Frontiers in plant science · 2024Article
- Interspecies transfer of RAMOSA1 orthologs and promoter cis sequences impacts maize inflorescence architecture.Plant physiology · 2023Article
- Article
- A high-resolution single-molecule sequencing-based Arabidopsis transcriptome using novel methods of Iso-seq analysis.Genome biology · 2022Article
- The Long Read Transcriptome of Rice (Oryza sativa ssp. japonica var. Nipponbare) Reveals Novel Transcripts.Rice (New York, N.Y.) · 2022Article
- Article
- An improved repertoire of splicing variants and their potential roles in Arabidopsis photomorphogenic development.Genome biology · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maize and sorghum are both important crops with similar overall plant architectures, but they have key differences, especially in regard to their inflorescences. To better understand these two organisms at the molecular level, we compared expression profiles of both protein-coding and noncoding transcripts in 11 matched tissues using single-molecule, long-read, deep RNA sequencing. This comparative analysis revealed large numbers of novel isoforms in both species. Evolutionarily young genes were likely to be generated in reproductive tissues and usually had fewer isoforms than old genes. We also observed similarities and differences in alternative splicing patterns and activities, both among tissues and between species. The maize subgenomes exhibited no bias in isoform generation; however, genes in the B genome were more highly expressed in pollen tissue, whereas genes in the A genome were more highly expressed in endosperm. We also identified a number of splicing events conserved between maize and sorghum. In addition, we generated comprehensive and high-resolution maps of poly(A) sites, revealing similarities and differences in mRNA cleavage between the two species. Overall, our results reveal considerable splicing and expression diversity between sorghum and maize, well beyond what was reported in previous studies, likely reflecting the differences in architecture between these two species.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.