Evidence map›Paper›PMID 29712753›Full record

ArticleGenome research2018

Birth, evolution, and transmission of satellite-free mammalian centromeric domains.

Solomon G Nergadze, Francesca M Piras, Riccardo Gamba, Marco Corbo, Federico Cerutti, Joseph G W McCarter, Eleonora Cappelletti, Francesco Gozzo, Rebecca M Harman, Douglas F Antczak and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
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  6. Review
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  8. Emergence of satellite DNAs suggests centromeric repositioning as a driver of karyotypic variation of the freshwater darter characines (Apareiodon affinis).Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026
    Article
  9. Article
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  13. CENP-A and centromere evolution in equids.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 4 countries.

Solomon G Nergadze *Department of Biology and Biotechnology "Lazzaro Spallanzani," University of Pavia, 27100 Pavia, Italy.
Francesca M Piras *Department of Biology and Biotechnology "Lazzaro Spallanzani," University of Pavia, 27100 Pavia, Italy.
Riccardo Gamba *Department of Biology and Biotechnology "Lazzaro Spallanzani," University of Pavia, 27100 Pavia, Italy.
Marco Corbo *Department of Biology and Biotechnology "Lazzaro Spallanzani," University of Pavia, 27100 Pavia, Italy.
Federico CeruttiDepartment of Biology and Biotechnology "Lazzaro Spallanzani," University of Pavia, 27100 Pavia, Italy.
Joseph G W McCarterCentre for Chromosome Biology, School of Natural Sciences, National University of Ireland, Galway, H91 TK33, Ireland.
Eleonora CappellettiDepartment of Biology and Biotechnology "Lazzaro Spallanzani," University of Pavia, 27100 Pavia, Italy.
Francesco GozzoDepartment of Biology and Biotechnology "Lazzaro Spallanzani," University of Pavia, 27100 Pavia, Italy.
Rebecca M HarmanBaker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York 14850, USA.
Douglas F AntczakBaker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York 14850, USA.
Donald MillerBaker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York 14850, USA.
Maren ScharfeGenomanalytik (GMAK), Helmholtz Centre for Infection Research (HZI), 38124 Braunschweig, Germany.
Giulio PavesiDepartment of Biosciences, University of Milano, 20122 Milano, Italy.
Elena RaimondiDepartment of Biology and Biotechnology "Lazzaro Spallanzani," University of Pavia, 27100 Pavia, Italy.
Kevin F SullivanCentre for Chromosome Biology, School of Natural Sciences, National University of Ireland, Galway, H91 TK33, Ireland.
Elena GiulottoDepartment of Biology and Biotechnology "Lazzaro Spallanzani," University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-4705-2049
University of Pavia · ITCornell University · USOllscoil na Gaillimhe – University of Galway · IEHelmholtz Centre for Infection Research · DEUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mammalian centromeres are associated with highly repetitive DNA (satellite DNA), which has so far hindered molecular analysis of this chromatin domain. Centromeres are epigenetically specified, and binding of the CENPA protein is their main determinant. In previous work, we described the first example of a natural satellite-free centromere on

Indexed as

Evolution, MolecularAnimalsAutoantigensCentromereCentromere Protein AChromatinDNA, SatelliteGenomic InstabilityHorsesMammalsAutoantigensCentromere Protein AChromatinDNA, Satellite

Identifiers

PMID29712753
PMCPMC5991519
OpenAlexW2801711428

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.