Evidence map›Paper›PMID 29712730›Full record

ArticleInfection and immunity2018

Pulmonary Surfactant Promotes Virulence Gene Expression and Biofilm Formation in Klebsiella pneumoniae.

Graham G Willsey, Sebastian Ventrone, Kristin C Schutz, Aaron M Wallace, John W Ribis, Benjamin T Suratt, Matthew J Wargo

Abstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. A laboratory perspective onFrontiers in microbiology · 2024
    Review
  8. Infection and immunity · 2023
    Article
  9. Article
  10. Regulation of biofilm formation inFrontiers in microbiology · 2023
    Review
  11. Article
  12. Frontiers in cellular and infection microbiology · 2022
    Review
  13. Article
  14. FromMicroorganisms · 2021
    Review
  15. Review
  16. Alveolar lipids in pulmonary disease. A review.Lipids in health and disease · 2020
    Review
  17. Article
  18. Article
  19. Article
  20. Journal of bacteriology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Graham G WillseyDepartment of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.
Sebastian VentroneDepartment of Medicine, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.
Kristin C SchutzDepartment of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.
Aaron M WallaceDepartment of Medicine, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.
John W RibisDepartment of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.
Benjamin T SurattThe Vermont Lung Center, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.
Matthew J WargoDepartment of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, Vermont, USA mwargo@uvm.edu.
University of Vermont · US

Funding

VERMONT IMMUNOBIOLOIGY/ INFECTIOUS DISEASES CENTERP20RR021905 · NCRR · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI HILL, JACK · 2006 to 2011
$14.5M
Vermont Immunology/Infectious Diseases CenterP30GM118228 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BUDD, RALPH C · 2016 to 2021
$6.8M
Multidisciplinary Training in Lung BiologyT32HL076122 · NHLBI · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI IRVIN, CHARLES G, POYNTER, MATTHEW E · 2004 to 2023
$6.1M
Pseudomonas detection and metabolism of sphingosineR01AI103003 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI WARGO, MATTHEW J · 2013 to 2017
$1.4M
Developing Obese Mouse Models of Pseudomonas Aeruginosa PneumoniaR03AI117069 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI WARGO, MATTHEW J · 2015 to 2016
$154k
NCRR NIH HHS P20 RR021905NHLBI NIH HHS T32 HL076122NIAID NIH HHS R01 AI103003NIAID NIH HHS R03 AI117069NIGMS NIH HHS P30 GM118228
6 · The paper itself

Abstract

The interactions between

Indexed as

Amino Acids, Branched-ChainAnimalsBiofilmsBiogenic PolyaminesFimbriae, BacterialGene Expression Regulation, BacterialHost-Pathogen InteractionsKlebsiella pneumoniaeMaleMiceMice, Inbred C57BLPulmonary SurfactantsVirulenceAmino Acids, Branched-ChainBiogenic PolyaminesPulmonary Surfactantscolonizationmetabolismpneumoniapolyaminespulmonary surfactantputrescinespermidinetype 3 fimbriae

Identifiers

PMID29712730
PMCPMC6013664
OpenAlexW2799366242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.