Evidence map›Paper›PMID 29712727›Full record

ArticleInfection and immunity2018

The Human Cathelicidin Antimicrobial Peptide LL-37 Promotes the Growth of the Pulmonary Pathogen Aspergillus fumigatus.

Gerard Sheehan, Gudmundur Bergsson, Noel G McElvaney, Emer P Reeves, Kevin Kavanagh

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. The Contribution of Human Antimicrobial Peptides to Fungi.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Antifungal Activity of Antimicrobial Peptides and Proteins againstJournal of fungi (Basel, Switzerland) · 2020
    Article
  8. Exposure ofJournal of fungi (Basel, Switzerland) · 2020
    Article
  9. Review
  10. Review
  11. Review
  12. LL37 InhibitsFrontiers in immunology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Gerard SheehanMedical Mycology Laboratory, Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland.
Gudmundur BergssonRespiratory Research Division, Department of Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Beaumont, Co. Dublin, Ireland.
Noel G McElvaneyRespiratory Research Division, Department of Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Beaumont, Co. Dublin, Ireland.
Emer P ReevesRespiratory Research Division, Department of Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Beaumont, Co. Dublin, Ireland.
Kevin KavanaghMedical Mycology Laboratory, Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland kevin.kavanagh@mu.ie.
National University of Ireland, Maynooth · IERoyal College of Surgeons in Ireland · IEBeaumont Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pulmonary mucus of cystic fibrosis (CF) patients displays elevated levels of the cathelicidin antimicrobial peptide LL-37, and the aim of this work was to assess the effect of LL-37 on the growth of

Indexed as

Antimicrobial Cationic PeptidesAspergillus fumigatusCathelicidinsCystic FibrosisHumansPulmonary AspergillosisAntimicrobial Cationic PeptidesCathelicidinsantimicrobial peptideAspergillus fumigatuscathelicidincystic fibrosisinnate immunityLL-37

Identifiers

PMID29712727
PMCPMC6013660
OpenAlexW2800583189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.