Evidence map›Paper›PMID 29712662›Full record

ArticleAntimicrobial agents and chemotherapy2018

Emergence of High-Level Colistin Resistance in an Acinetobacter baumannii Clinical Isolate Mediated by Inactivation of the Global Regulator H-NS.

Deanna Deveson Lucas, Bethany Crane, Amy Wright, Mei-Ling Han, Jennifer Moffatt, Dieter Bulach, Simon L Gladman, David Powell, Jesus Aranda, Torsten Seemann and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Acquired mutations in transcriptional regulatorAntimicrobial agents and chemotherapy · 2026
    Article
  3. Article
  4. Molecular Characterization of Colistin-Resistant ClinicalAntibiotics (Basel, Switzerland) · 2026
    Article
  5. Resistance, heteroresistance, and fitness costs drive colistin treatment failure duringProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. H-NS controls the susceptibility ofFrontiers in veterinary science · 2025
    Article
  8. Review
  9. Treatment Strategies of Colistin ResistanceAntibiotics (Basel, Switzerland) · 2024
    Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Colistin Resistance inAntibiotics (Basel, Switzerland) · 2023
    Review
  15. Comparative genomics and molecular epidemiology of colistin-resistantComputational and structural biotechnology journal · 2023
    Article
  16. Retained colistin susceptibility in clinicalFrontiers in cellular and infection microbiology · 2023
    Article
  17. Frontiers in microbiology · 2023
    Review
  18. Deciphering the virulence factors, regulation, and immune response toFrontiers in cellular and infection microbiology · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

Deanna Deveson LucasInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Victoria, Australia.
Bethany CraneInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Victoria, Australia.
Amy WrightInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Victoria, Australia.
Mei-Ling HanDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Jennifer MoffattInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Victoria, Australia.
Dieter BulachMonash Bioinformatics Platform, Monash University, Victoria, Australia.
Simon L GladmanMonash Bioinformatics Platform, Monash University, Victoria, Australia.
David PowellMonash Bioinformatics Platform, Monash University, Victoria, Australia.
Jesus ArandaInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Victoria, Australia.
Torsten SeemannMonash Bioinformatics Platform, Monash University, Victoria, Australia.
Diana MachadoGlobal Health and Tropical Medicine, GHTM, Instituto de Higiene e Medicina Tropical, IHMT, Universidade Nova de Lisboa, UNL, Lisbon, Portugal.
Teresa PachecoClinical Pathology Service, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal.
Teresa MarquesClinical Pathology Service, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal.
Miguel ViveirosGlobal Health and Tropical Medicine, GHTM, Instituto de Higiene e Medicina Tropical, IHMT, Universidade Nova de Lisboa, UNL, Lisbon, Portugal.
Roger NationDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Jian LiInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Victoria, Australia.
Marina HarperInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Victoria, Australia.
John D BoyceInfection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Microbiology, Monash University, Victoria, Australia john.boyce@monash.edu.ORCID 0000-0002-8614-3074
Australian Regenerative Medicine Institute · AUMonash University · AUCentro Hospitalar de Lisboa Ocidental · PTUniversidade Nova de Lisboa · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colistin is a crucial last-line drug used for the treatment of life-threatening infections caused by multidrug-resistant strains of the Gram-negative bacterium

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsBacterial ProteinsColistinDrug Resistance, BacterialEthanolaminephosphotransferaseGene Expression ProfilingMicrobial Sensitivity TestsPhylogenyReverse Transcriptase Polymerase Chain ReactionAnti-Bacterial AgentsBacterial ProteinsColistinEthanolaminephosphotransferaseAcinetobacterantibiotic resistancecolistinH-NSinsertion sequencephosphoethanolamine transferase

Identifiers

PMID29712662
PMCPMC6021671
OpenAlexW2799805438

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.