Evidence map›Paper›PMID 29712621›Full record

ArticleJMIR public health and surveillance2018

Incidence of Lower Respiratory Tract Infections and Atopic Conditions in Boys and Young Male Adults: Royal College of General Practitioners Research and Surveillance Centre Annual Report 2015-2016.

Simon de Lusignan, Ana Correa, Richard Pebody, Ivelina Yonova, Gillian Smith, Rachel Byford, Sameera Rankiri Pathirannehelage, Christopher McGee, Alex J Elliot, Mariya Hriskova and 3 more

Open access · goldAbstract read
In one paragraph

Article in JMIR public health and surveillance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. The epidemiology of eczema in children and adults in England: A population-based study using primary care data.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Simon de Lusignan *Department of Clinical and Experimental Medicine, University of Surrey, Guildford, United Kingdom.ORCID http://orcid.org/0000-0002-8553-2641
Ana CorreaDepartment of Clinical and Experimental Medicine, University of Surrey, Guildford, United Kingdom.ORCID http://orcid.org/0000-0002-0988-061X
Richard PebodyRespiratory Diseases Department, National Infection Service, Public Health England, London, United Kingdom.ORCID http://orcid.org/0000-0002-9069-2885
Ivelina YonovaDepartment of Clinical and Experimental Medicine, University of Surrey, Guildford, United Kingdom.ORCID http://orcid.org/0000-0003-4856-3075
Gillian SmithReal-time Syndromic Surveillance Team, National Infection Service, Public Health England, Birmingham, United Kingdom.ORCID http://orcid.org/0000-0002-4257-0568
Rachel ByfordDepartment of Clinical and Experimental Medicine, University of Surrey, Guildford, United Kingdom.ORCID http://orcid.org/0000-0002-4792-8995
Sameera Rankiri PathirannehelageDepartment of Clinical and Experimental Medicine, University of Surrey, Guildford, United Kingdom.ORCID http://orcid.org/0000-0002-5112-8296
Christopher McGeeDepartment of Clinical and Experimental Medicine, University of Surrey, Guildford, United Kingdom.ORCID http://orcid.org/0000-0002-9964-4724
Alex J ElliotReal-time Syndromic Surveillance Team, National Infection Service, Public Health England, Birmingham, United Kingdom.ORCID http://orcid.org/0000-0002-6414-3065
Mariya HriskovaDepartment of Clinical and Experimental Medicine, University of Surrey, Guildford, United Kingdom.ORCID http://orcid.org/0000-0002-4336-255X
Filipa Im FerreiraDepartment of Clinical and Experimental Medicine, University of Surrey, Guildford, United Kingdom.ORCID http://orcid.org/0000-0002-7717-8486
Imran RafiClinical Innovation and Research Centre, Royal College of General Practitioners, London, United Kingdom.ORCID http://orcid.org/0000-0001-9673-9675
Simon JonesDepartment of Clinical and Experimental Medicine, University of Surrey, Guildford, United Kingdom.ORCID http://orcid.org/0000-0002-8267-5647
University of Surrey · GBPublic Health England · GBRoyal College of General Practitioners · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Royal College of General Practitioners Research and Surveillance Centre comprises more than 150 general practices, with a combined population of more than 1.5 million, contributing to UK and European public health surveillance and research.

objectiveThe aim of this paper was to report gender differences in the presentation of infectious and respiratory conditions in children and young adults.

methodsDisease incidence data were used to test the hypothesis that boys up to puberty present more with lower respiratory tract infection (LRTI) and asthma. Incidence rates were reported for infectious conditions in children and young adults by gender. We controlled for ethnicity, deprivation, and consultation rates. We report odds ratios (OR) with 95% CI, P values, and probability of presenting.

resultsBoys presented more with LRTI, largely due to acute bronchitis. The OR of males consulting was greater across the youngest 3 age bands (OR 1.59, 95% CI 1.35-1.87; OR 1.13, 95% CI 1.05-1.21; OR 1.20, 95% CI 1.09-1.32). Allergic rhinitis and asthma had a higher OR of presenting in boys aged 5 to 14 years (OR 1.52, 95% CI 1.37-1.68; OR 1.31, 95% CI 1.17-1.48). Upper respiratory tract infection (URTI) and urinary tract infection (UTI) had lower odds of presenting in boys, especially those older than 15 years. The probability of presenting showed different patterns for LRTI, URTI, and atopic conditions.

conclusionsBoys younger than 15 years have greater odds of presenting with LRTI and atopic conditions, whereas girls may present more with URTI and UTI. These differences may provide insights into disease mechanisms and for health service planning.

Indexed as

asthmabronchitiscommon coldconjunctivitisgastroenteritisgeneral practicemedical record system, Computerizedpharyngitispopulation surveillancerhinitisurinary tract infections

Identifiers

PMID29712621
PMCPMC5952117
OpenAlexW2800993033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.