ArticleMolecules (Basel, Switzerland)2018
Synthesis of a Novel Series of Amino Acid Prodrugs Based on Thienopyridine Scaffolds and Evaluation of Their Antiplatelet Activity.
Nan Lu, Lingjun Li, Xuemin Zheng, Shijun Zhang, Yuquan Li, Jing Yuan, Qunchao Wei, Youjun Xu, Fancui Meng
Open access · goldAbstract readComparative Study
In one paragraphArticle in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 6 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
9 authors at 2 institutions in 1 country.
Nan LuSchool of Pharmaceutical Engineering, and Key Laboratory of Structure-Based Drug Design & Discovery (Ministry of Education), Shenyang Pharmaceutical University, Shenyang 110016, China. lunantj@126.com.ORCID 0000-0002-2170-2736 Lingjun LiTianjin Key Laboratory of Molecular Design and Drug Discovery, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China. lilj@tjipr.com.
Xuemin ZhengTianjin Key Laboratory of Molecular Design and Drug Discovery, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China. zhengxm@tjipr.com.
Shijun ZhangTianjin Key Laboratory of Molecular Design and Drug Discovery, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China. zhangsj@tjipr.com.
Yuquan LiTianjin Key Laboratory of Molecular Design and Drug Discovery, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China. liyq@tjipr.com.
Jing YuanTianjin Key Laboratory of Molecular Design and Drug Discovery, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China. yuanj@tjipr.com.
Qunchao WeiTianjin Key Laboratory of Molecular Design and Drug Discovery, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China. weiqc@tjipr.com.
Youjun XuSchool of Pharmaceutical Engineering, and Key Laboratory of Structure-Based Drug Design & Discovery (Ministry of Education), Shenyang Pharmaceutical University, Shenyang 110016, China. xuyoujun@syphu.edu.cn.
Fancui MengTianjin Key Laboratory of Molecular Design and Drug Discovery, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China. mengfc@tjipr.com.ORCID 0000-0002-5064-0618 Tianjin Institute of Pharmaceutical Research (China) · CNShenyang Pharmaceutical University · CN
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
The thienopyridines class of drugs used as P2Y
Indexed as
Adenosine DiphosphateAnimalsBleeding TimeClopidogrelDisease Models, AnimalDose-Response Relationship, DrugMaleMolecular StructurePlatelet AggregationPrasugrel HydrochlorideProdrugsRatsThienopyridinesTiclopidineAdenosine DiphosphateClopidogrelPrasugrel HydrochlorideProdrugsThienopyridinesTiclopidineADP-induced platelet aggregationamino acid prodrugsantiplateletP2Y12 receptor antagonistthienopyridines
Identifiers
PMID29710801
PMCPMC6102589
OpenAlexW2800465524
What OpenQuestion holds
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LicenceCC BY
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