Evidence map›Paper›PMID 29710799›Full record

ArticleInternational journal of molecular sciences2018

Metal Free Graphene Oxide (GO) Nanosheets and Pristine-Single Wall Carbon Nanotubes (p-SWCNTs) Biocompatibility Investigation: A Comparative Study in Different Human Cell Lines.

Federica Valentini, Emanuela Mari, Alessandra Zicari, Andrea Calcaterra, Maurizio Talamo, Maria Giovanna Scioli, Augusto Orlandi, Stefania Mardente

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. RSC advances · 2022
    Review
  7. Article
  8. Graphene Nanomaterials: Synthesis, Biocompatibility, and Cytotoxicity.International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Federica ValentiniDepartment of Sciences and Chemical Technologies, University of Rome Tor Vergata, via della Ricerca Scientifica 1, 00133 Rome, Italy. federica.valentini@uniroma2.it.
Emanuela MariDepartment of Experimental Medicine, University of Rome Sapienza, Viale Regina Elena 324, 00161 Rome, Italy. emanuela.mari@uniroma1.it.
Alessandra ZicariDepartment of Experimental Medicine, University of Rome Sapienza, Viale Regina Elena 324, 00161 Rome, Italy. alessandra.zicari@uniroma1.it.
Andrea CalcaterraINUIT Foundation, University of Roma Tor Vergata, via dell'Archigginasio, 00133 Rome, Italy. andrea.calcaterra@uniroma2.it.
Maurizio TalamoINUIT Foundation, University of Roma Tor Vergata, via dell'Archigginasio, 00133 Rome, Italy. maurizio.talamo@uniroma2.it.
Maria Giovanna ScioliDepartment of Medicine, Pathological Anatomy, University of Rome Tor Vergata, Viale Oxford 81, 00133 Rome, Italy. scioli07@hotmail.it.
Augusto OrlandiDepartment of Medicine, Pathological Anatomy, University of Rome Tor Vergata, Viale Oxford 81, 00133 Rome, Italy. augusto.orlandi@uniroma2.it.
Stefania MardenteDepartment of Experimental Medicine, University of Rome Sapienza, Viale Regina Elena 324, 00161 Rome, Italy. stefania.mardente@uniroma1.it.
Sapienza University of Rome · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The in vitro biocompatibility of Graphene Oxide (GO) nanosheets, which were obtained by the electrochemical exfoliation of graphite electrodes in an electrolytic bath containing salts, was compared with the pristine Single Wall Carbon Nanotubes (p-SWCNTs) under the same experimental conditions in different human cell lines. The cells were treated with different concentrations of GO and SWCNTs for up to 48 h. GO did not induce any significant morphological or functional modifications (demonstrating a high biocompatibility), while SWNCTs were toxic at any concentration used after a few hours of treatment. The cell viability or cytotoxicity were detected by the trypan blue assay and the

Indexed as

Biocompatible MaterialsCell DeathCell NucleusCytoplasmGraphiteHeLa CellsHumansHuman Umbilical Vein Endothelial CellsNanotubes, CarbonSpecies SpecificityVacuolesBiocompatible MaterialsGraphiteNanotubes, Carbonbiocompatibilitycytotoxicitygraphene oxideLDHp-SWCNTs

Identifiers

PMID29710799
PMCPMC5983736
OpenAlexW2802021904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.