Evidence map›Paper›PMID 29710774›Full record

ArticleMolecules (Basel, Switzerland)2018

Discovery of Pyrazolo[4,3-

Chih-Hua Tseng, Chun-Wei Tung, Shin-I Peng, Yeh-Long Chen, Cherng-Chyi Tzeng, Chih-Mei Cheng

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 22 citations in OpenAlex.

  1. Synthesis andCurrent topics in medicinal chemistry · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chih-Hua TsengSchool of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung City 807, Taiwan. chihhua@kmu.edu.tw.
Chun-Wei TungSchool of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung City 807, Taiwan. cwtung@kmu.edu.tw.ORCID 0000-0003-3011-8440
Shin-I PengDepartment of Medicinal and Applied Chemistry, College of Life Science, Kaohsiung Medical University, Kaohsiung City 807, Taiwan. andrea6599@gmail.com.
Yeh-Long ChenDepartment of Medicinal and Applied Chemistry, College of Life Science, Kaohsiung Medical University, Kaohsiung City 807, Taiwan. yeloch@kmu.edu.tw.
Cherng-Chyi TzengDepartment of Medicinal and Applied Chemistry, College of Life Science, Kaohsiung Medical University, Kaohsiung City 807, Taiwan. tzengch@kmu.edu.tw.
Chih-Mei ChengDepartment of Biomedical Science and Environmental Biology, College of Life Science, Kaohsiung Medical University, Kaohsiung City 807, Taiwan. chmech@kmu.edu.tw.
Kaohsiung Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synthesis and anti-inflammatory effects of certain pyrazolo[4,3-

Indexed as

AnimalsAnti-Inflammatory AgentsCyclooxygenase 2Down-RegulationGene Expression Regulation, EnzymologicLipopolysaccharidesMacrophagesMiceModels, MolecularNitric OxideNitric Oxide Synthase Type IIPyrazolesQuantitative Structure-Activity RelationshipQuinolinesRAW 264.7 CellsAnti-Inflammatory AgentsCyclooxygenase 2LipopolysaccharidesNitric OxideNitric Oxide Synthase Type IINos2 protein, mousePtgs2 protein, mousePyrazolesQuinolinesanti-inflammatory activitynitric oxidepyrazolo[4,3-c]quinolines

Identifiers

PMID29710774
PMCPMC6102577
OpenAlexW2802356907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.