Evidence map›Paper›PMID 29710746›Full record

ArticleTechnology and health care : official journal of the European Society for Engineering and Medicine2018

Effect of 405 nm low intensity irradiation on the absorption spectrum of in-vitro hyperlipidemia blood.

Hong Wang, Weichao Liu, Xiang Fang, Haichen Wang, Wenjiang Ma, Huajiang Dong, Huijuan Yin, Ying-Xin Li, Hong Sha

Open access · bronzeAbstract read
In one paragraph

Article in Technology and health care : official journal of the European Society for Engineering and Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Under the spotlight: mechanisms of photobiomodulation concentrating on blue and green light.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2019
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hong WangChinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China.
Weichao LiuChinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China.
Xiang FangChinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China.
Haichen WangChinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China.
Wenjiang MaTianjin Medical University Eye Hospital, Tianjin 300384, China.
Huajiang DongState Key Laboratory of Precision Measurement Technology and Instruments, Tianjin University, Tianjin 300072, China.
Huijuan YinChinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China.
Ying-Xin LiChinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China.
Hong ShaChinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNTianjin Medical University Eye Hospital · CNTianjin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaser therapy is reported to be clinically effective for improving microcirculation, rheological properties and blood lipid profiles despite the lack of certainty on the mechanism.

objectiveThis study intends to provide methods to drop blood lipid level of hyperlipidemia samples by low-intensity laser irradiation therapy and provide reasoning of mechanism.

methodsTwenty whole blood samples of high level of lipids profile are irradiated by 405 nm low-intensity laser at 12 J/cm2 twice a day for 3 days and compared with normal lipids profile group. Then whole blood sample are centrifuged to obtain result of erythrocyte for further interpretation. Multi-scan spectrum microplate reader is used to measure absorption spectrum and data is analyzed by software SPSS 14.0.

resultsResults show that after 405 nm low-intensity laser irradiation, whole blood samples of high lipid level statistically have higher absorbance peak value than normal samples while erythrocyte samples have lower absorbance peak value.

conclusionsFrom the divergence of absorption peak value change after low-intensity laser irradiation for whole blood sample and erythrocyte, we suspect that low level laser irradiation affects the enzymes activity of lipid metabolism, improves the cholesterol balance of plasma and cytoplasm in erythrocyte, and decreases aggregation of the erythrocyte.

Indexed as

AdultAgedAged, 80 and overErythrocytesFemaleHumansHyperlipidemiasIn Vitro TechniquesLow-Level Light TherapyMaleMiddle AgedSpectrum AnalysisLow-intensity laser irradiation; absorption spectrometry; lipid profile; erythrocyte membrane

Identifiers

PMID29710746
PMCPMC6004948
OpenAlexW2801467927

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.