Evidence map›Paper›PMID 29709950›Full record

ArticleInternal medicine (Tokyo, Japan)2018

An Autopsy Case of Myeloperoxidase-anti-neutrophil Cytoplasmic Antibody (MPO-ANCA)-associated Vasculitis Accompanied by Cryoglobulinemic Vasculitis Affecting the Kidneys, Skin, and Gastrointestinal Tract.

Jumpei Hasegawa, Sachiko Wakai, Momoko Kono, Yusuke Imaizumi, Sakiko Masuda, Akihiro Ishizu, Kazuho Honda

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jumpei HasegawaDepartment of Nephrology, Tokyo Metropolitan Health and Medical Treatment Corporation Okubo Hospital, Japan.
Sachiko WakaiDepartment of Nephrology, Tokyo Metropolitan Health and Medical Treatment Corporation Okubo Hospital, Japan.
Momoko KonoDepartment of Nephrology, Tokyo Metropolitan Health and Medical Treatment Corporation Okubo Hospital, Japan.
Yusuke ImaizumiDepartment of Nephrology, Tokyo Metropolitan Health and Medical Treatment Corporation Okubo Hospital, Japan.
Sakiko MasudaFaculty of Health Sciences, Hokkaido University, Japan.
Akihiro IshizuFaculty of Health Sciences, Hokkaido University, Japan.
Kazuho HondaDepartment of Anatomy, Showa University School of Medicine, Japan.
Ohkubo Hospital · JPHealth Sciences University of Hokkaido · JPHokkaido University · JPShowa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and cryoglobulinemic vasculitis (CV) rarely coexist. An 83-year-old woman was admitted with rapidly progressive renal failure, gastrointestinal hemorrhage and purpura with myeloperoxidase (MPO)-ANCA positivity and cryoglobulinemia. Despite intensive immunosuppressive treatment, she died of aspergillus pneumonia. Autopsy revealed necrotizing crescentic glomerulitis in the majority of the glomeruli, accompanied by partially membranoproliferative-like glomerular changes. Immunofluorescence staining revealed the presence of neutrophil extracellular trap (NET) formation in the glomeruli and cutaneous arteries. These pathological findings suggested that MPO-AAV and/or CV caused NET formation, leading to lethal systemic vasculitis.

Indexed as

Aged, 80 and overAnti-Neutrophil Cytoplasmic Antibody-Associated VasculitisAutopsyCryoglobulinemiaExtracellular TrapsFatal OutcomeFemaleGastrointestinal TractGlomerulonephritisHumansKidneyKidney GlomerulusPeroxidaseSkinSystemic VasculitisPeroxidaseANCAanti-neutrophil cytoplasmic antibodycryoglobulinNETsneutrophil extracellular trapsvasculitis

Identifiers

PMID29709950
PMCPMC6191583
OpenAlexW2801937332

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.