Evidence map›Paper›PMID 29709526›Full record

ReviewGastrointestinal endoscopy2018

Screening for esophageal squamous cell carcinoma: recent advances.

Don C Codipilly, Yi Qin, Sanford M Dawsey, John Kisiel, Mark Topazian, David Ahlquist, Prasad G Iyer

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Gastrointestinal endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07266363 (SYNERGY Study), which is not on this map. Cited by 143 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
143citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07266363 recruitingnot on this mapstarted 2025, after this paper: background citation

SYNERGY Study: Early Detection Through Integrated Evaluation of Cell-Free and Exosomal microRNAs for Biomarker-Guided Screening of Esophageal Squamous Cell Carcinoma

TypeobservationalSponsorCity of Hope Medical CenterRan2025 to 2028Enrolled600ConditionsESCCArmsSmall RNA sequencing of exo- and cf-miRNAs, RT-qPCR quantification of cf- and exo-miRNAs (SYNERGY assay), PCR-based validation (SYNERGY assay)
3 · Its place in the literature

Who cites it

143 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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83 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Don C CodipillyDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
Yi QinDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
Sanford M DawseyDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland.
John KisielDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
Mark TopazianDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
David AhlquistDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
Prasad G IyerDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.

Funding

Upper Gastrointestinal Cancer StudiesZIACP000185 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ABNET, CHRISTIAN · 2009 to 2025
$25.6M
Upper Gastrointestinal Cancer StudiesZ01CP000185 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI DAWSEY, SANFORD M · 2005 to 2008
$1.4M
Intramural NIH HHS Z01 CP000185
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Early Detection of CancerEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaEsophagoscopyHumansPopulation Surveillance

Identifiers

PMID29709526
PMCPMC7493990

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.