Evidence map›Paper›PMID 29709519›Full record

ArticleReproductive toxicology (Elmsford, N.Y.)2018

Cardiopulmonary consequences of gestational toxicant exposure: Symposium overview at the 56th annual SOT meeting, Baltimore, MD.

Phoebe A Stapleton, Christopher J Wingard, Timothy R Nurkiewicz, Alison C Holloway, Judith T Zelikoff, Thomas B Knudsen, Lynette K Rogers

Abstract readConference Proceedings
PubMed Full text at PMC Publisher
In one paragraph

Article in Reproductive toxicology (Elmsford, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trimester-specific exposure to PMBMC pregnancy and childbirth · 2026
    Article
  2. Observational
  3. Article
  4. Prenatal Exposure toEnvironmental health perspectives · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Phoebe A StapletonDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ, USA. Electronic address: stapleton@eohsi.rutgers.edu.
Christopher J WingardCollege of Health Professions, School of Movement and Rehabilitation Sciences, Bellarmine University, Louisville, KY, USA.
Timothy R NurkiewiczDepartment of Physiology, Pharmacology, and Neuroscience, Toxicology Working Group, West Virginia University, Morgantown, WV, USA.
Alison C HollowayDepartment of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada.
Judith T ZelikoffNew York University School of Medicine, Dept. of Environmental Medicine, 57 Old Forge Road, Tuxedo, NY, USA.
Thomas B KnudsenNational Center for Computational Toxicology, US Environmental Protection Agency, Research Triangle Park, NC, USA.
Lynette K RogersCenter for Perinatal Research, The Research Institute at Nationwide Children's Hospital, The Ohio State University, Columbus, OH, USA. Electronic address: Lynette.Rogers@Nationwidechildrens.org.

Funding

Mitochondrial Mechanisms, Microvascular Function, and Gestational NanotoxicologyR00ES024783 · NIEHS · RUTGERS, THE STATE UNIV OF N.J. · PI STAPLETON, PHOEBE · 2017 to 2019
$747k
NIEHS NIH HHS R00 ES024783
6 · The paper itself

Abstract

Xenobiotic exposures affect the maternal and/or in utero environment resulting in impairments in fetal development. During the period of rapid fetal growth, developing cardiovascular systems are especially vulnerable to their environment. Furthermore, fetal exposures can evoke changes in epigenetic signatures that result in permanent modifications in gene expression. This symposium focused on the intersection between maternal and fetal exposure and the developing cardiovascular system. The impact of maternal exposures on prenatal development is of major concern for regulatory agencies given the unique vulnerability of the embryo/fetus to environmental factors, the importance of vascular biology to maternal-fetal interactions, and the adverse consequences of vascular disruption to children's health. Speakers provided data from diverse exposures: nanomaterials, particulate matter or air pollution (PM

Indexed as

AnimalsCardiovascular SystemEnvironmental PollutantsFemaleFetal DevelopmentHumansMaternal ExposureMaternal-Fetal ExchangeNanostructuresPlacentaPregnancyXenobioticsEnvironmental PollutantsXenobioticsCardiovascularIn utero toxicityMaternal exposures

Identifiers

PMID29709519
PMCPMC6642064

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.