Evidence map›Paper›PMID 29708836›Full record

ReviewHuman vaccines & immunotherapeutics2018

Development of new hepatitis E vaccines.

Yufeng Cao, Zhenhong Bing, Shiyu Guan, Zecai Zhang, Xinping Wang

Open access · bronzeAbstract readHistorical ArticleReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Viral Replicon Systems and Their Biosafety Aspects.Applied biosafety : journal of the American Biological Safety Association · 2023
    Review
  10. Article
  11. Virus-like particle vaccinology, from bench to bedside.Cellular & molecular immunology · 2022
    Review
  12. [Vaccines against hepatitis E virus: state of development].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Viral hepatitis and pregnancy.Nature reviews. Gastroenterology & hepatology · 2021
    Review
  17. Review
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Yufeng Caoa College of Veterinary Medicine, Jilin University , Changchun , Jilin , PR China.
Zhenhong Bingc Changchun Institute of Biological Products , Changchun , Jilin , PR China.
Shiyu Guanc Changchun Institute of Biological Products , Changchun , Jilin , PR China.
Zecai Zhanga College of Veterinary Medicine, Jilin University , Changchun , Jilin , PR China.
Xinping Wanga College of Veterinary Medicine, Jilin University , Changchun , Jilin , PR China.
Jilin University · CNChangchun Institute of Biological Products · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis E virus (HEV) infection is an emerging zoonotic disease posing a severe threat to public health in the world, especially to pregnant women. Currently, no specific treatments are available for HEV infection. Therefore, it is crucial to develop vaccine to prevent this infection. Although several potential candidate vaccines against HEV have been studied for their immunogenicity and efficacy, only Hecolin® which is developed by Xiamen Innovax Biotech Co., Ltd. and approved by China Food and Drug Administration (CFDA) in 2012, is the licensed HEV vaccine in the world so far. Extensive studies on safety, immunogenicity and efficacy in phase III clinical trials have shown that Hecolin® is a promising vaccine for HEV prevention and control. In this article, the advances on HEV vaccine development and research are briefly reviewed.

Indexed as

ChinaClinical Trials, Phase III as TopicDisease Transmission, InfectiousDrug DevelopmentHepatitis EHepatitis E virusHistory, 21st CenturyHumansTreatment OutcomeVaccines, SyntheticViral Hepatitis VaccineshecolinVaccines, SyntheticViral Hepatitis VaccinesAdvanceHepatitis EHEVVaccine

Identifiers

PMID29708836
PMCPMC6183316
OpenAlexW2800038274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.