Evidence map›Paper›PMID 29708401›Full record

ArticleCNS oncology2018

Patterns of care and treatment outcomes of patients with astroblastoma: a National Cancer Database analysis.

Emily C Merfeld, Sonika Dahiya, Stephanie M Perkins

Open access · goldAbstract read
In one paragraph

Article in CNS oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A case of disseminated spinal astroblastoma harboring a MAMLD1::BEND2 fusion.Neuropathology : official journal of the Japanese Society of Neuropathology · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Malignant AstroblastomaBalkan medical journal · 2020
    Article
  10. Article
  11. Posterior fossa astroblastoma in a child: a case report and a review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Emily C MerfeldDepartment of Radiation Oncology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110 USA.
Sonika DahiyaDepartment of Pathology & Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110 USA.
Stephanie M PerkinsDepartment of Radiation Oncology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110 USA.
Washington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the use of chemotherapy and radiation, and their outcomes for patients with astroblastoma. PATIENTS &

methodsThis is a retrospective review of patients extracted from the National Cancer Database. We investigated overall survival (OS) using Kaplan-Meier curves. Cox proportional hazards models were used to correlate OS with risk variables and treatments.

resultsOS at 5 years was 79.5%. Patients with high-grade tumors were more likely to receive chemotherapy and radiation. Patients with high-grade astroblastoma who did not receive adjuvant radiation had poor survival.

conclusionPatients with astroblastoma should be treated with curative intent. Radiation is likely beneficial in high-grade astroblastoma. The exact role of radiation and chemotherapy following surgical resection warrant further investigation.

Indexed as

AdolescentAdultBrain NeoplasmsChildChild, PreschoolFollow-Up StudiesHumansInfantInfant, NewbornNeoplasm GradingNeoplasms, NeuroepithelialRetrospective StudiesSurvival AnalysisTreatment OutcomeYoung Adultastroblastomabrain tumorneuro-oncologypediatric oncologyrare tumor

Identifiers

PMID29708401
PMCPMC5977281
OpenAlexW2799468502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.