Evidence map›Paper›PMID 29708212›Full record

ArticleEuropean radiology experimental2018

Myocardial tissue characterization by combining late gadolinium enhancement imaging and percent edema mapping: a novel T2 map-based MRI method in canine myocardial infarction.

Pal Suranyi, Gabriel A Elgavish, U Joseph Schoepf, Balazs Ruzsics, Pal Kiss, Marly van Assen, Brian E Jacobs, Brigitta C Brott, Ada Elgavish, Akos Varga-Szemes

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European radiology experimental, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Pal Suranyi1Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Dr, Charleston, SC 29425 USA.
Gabriel A Elgavish2Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, MCLM 556, Birmingham, AL 35294-0005 USA.
U Joseph Schoepf1Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Dr, Charleston, SC 29425 USA.
Balazs Ruzsics3Department of Cardiology, Royal Liverpool and Broadgreen University Hospital, Thomas Dr, Liverpool, L14 3LB UK.
Pal Kiss2Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, MCLM 556, Birmingham, AL 35294-0005 USA.
Marly van Assen1Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Dr, Charleston, SC 29425 USA.
Brian E Jacobs1Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Dr, Charleston, SC 29425 USA.
Brigitta C Brott5Department of Medicine, Division of Cardiovascular Disease, University of Alabama at Birmingham, FOT 907, Birmingham, AL 35294-3407 USA.
Ada Elgavish6Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, MCLM 556, Birmingham, AL 35294-0005 USA.
Akos Varga-Szemes1Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Dr, Charleston, SC 29425 USA.ORCID 0000-0002-2781-7462
Medical University of South Carolina · USUniversity of Alabama at Birmingham · USRoyal Liverpool and Broadgreen University Hospital NHS Trust · GBUniversity Medical Center Groningen · NL

Funding

Persistent Contrast Agent for Percent Infarct Map in MRIR41HL084795 · NHLBI · ELGAVISH PARAMAGNETICS, INC. · PI SURANYI, PAL · 2006 to 2006
$129k
MRI Quantification of Postinfarct Myocardial ViabilityR41HL080886 · NHLBI · ELGAVISH PARAMAGNETICS, INC. · PI SURANYI, PAL · 2005 to 2005
$100k
NHLBI NIH HHS R41 HL080886NHLBI NIH HHS R41 HL084795
6 · The paper itself

Abstract

backgroundAssessing the extent of ischemic and reperfusion-associated myocardial injuries remains challenging with current magnetic resonance imaging (MRI) techniques. Our aim was to develop a tissue characterization mapping (TCM) technique by combining late gadolinium enhancement (LGE) with our novel percent edema mapping (PEM) approach to enable the classification of tissue represented by MRI voxels as healthy, myocardial edema (ME), necrosis, myocardial hemorrhage (MH), or scar.

methodsSix dogs underwent closed-chest myocardial infarct (MI) generation. Serial MRI scans were performed post-MI on days 3, 4, 6, 14, and 56, including T2 mapping and LGE. Dogs were sacrificed on day 4 (

resultsThe MI, ME, and MH measured by TCM were 13.4% [25

conclusionsPreliminary results suggest that the TCM method is feasible for the in vivo localization and quantification of various MI-related tissue components.

Indexed as

Magnetic resonance imagingMyocardial edemaMyocardial hemorrhageMyocardial infarctionTissue characterization

Identifiers

PMID29708212
PMCPMC5909369
OpenAlexW2801535299

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.