ArticleEuropean radiology experimental2018
Optical imaging of the breast: evaluation of deoxyhemoglobin concentration alteration in 166 patients with suspicious breast lesions.
Article in European radiology experimental, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 6 citations in OpenAlex.
- A diagnostic test evaluation: dynamic optical functional imaging system for early-stage breast cancer detection.Translational cancer research · 2025Article
- Detection of breast cancer using machine learning on time-series diffuse optical transillumination data.Journal of biomedical optics · 2024Article
- Intelligent scoring system based on dynamic optical breast imaging for early detection of breast cancer.Biomedical optics express · 2024Article
- Recent Advances in Ultrasound Breast Imaging: From Industry to Clinical Practice.Diagnostics (Basel, Switzerland) · 2023Review
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11 authors at 1 institution in 1 country.
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Abstract
backgroundWe investigated the performance of optical imaging evaluating deoxyhemoglobin concentration alteration (DeHCA) in breast tissues.
methodsWe enrolled all consecutive patients from January 2015 to October 2016 with clinically suspicious and/or BI-RADS grade 3-5 lesions at mammography or ultrasound (US). Patients underwent optical imaging (ComfortScan) to evaluate for DeHCA. The reference standard was pathology from a surgical specimen for malignant lesions, pathology from a surgical specimen or core needle biopsy for benign lesions, and negative follow-up for contralateral negative breasts. Non-parametric statistics, receiver operating characteristic, and linear discrimination analyses were performed.
resultsOf 334 enrolled patients, 168 (50%) were excluded for technical problems and 166 (50%) (median age 52 years) were analyzed totaling 331 breasts and 176 lesions. Of these, 75 were benign (median size 19 mm) and 101 malignant (median size 20 mm). The median DeHCA score in malignant lesions (0.95, interquartile range [IQR] 1.00-0.87) was higher (
conclusionsDeHCA score was significantly higher in malignant than in benign lesions, but its accuracy was significantly lower than that of mammography or US. Future refinements are needed.
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