Evidence map›Paper›PMID 29708019›Full record

ArticlePulmonary circulation

Measuring pulmonary arterial compliance: mission impossible? Insights from a novel in vivo continuous-flow based experimental model.

Frédéric Vanden Eynden, Thierry Bové, Marie-Luce Chirade, Guido Van Nooten, Patrick Segers

Abstract read
In one paragraph

Article in Pulmonary circulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Pulmonary arterial compliance as a measure of right ventricular loading in mitral regurgitation.International journal of cardiology. Heart & vasculature · 2024
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Frédéric Vanden Eynden1 Cardiac Surgery, Université Libre de Bruxelles, Hôpital Académique Erasme, Brussels, Belgium.
Thierry Bové2 Laboratory of Experimental Cardiac Surgery, Ghent University Hospital, Belgium.
Marie-Luce Chirade1 Cardiac Surgery, Université Libre de Bruxelles, Hôpital Académique Erasme, Brussels, Belgium.
Guido Van Nooten1 Cardiac Surgery, Université Libre de Bruxelles, Hôpital Académique Erasme, Brussels, Belgium.
Patrick Segers3 IBiTech-bioMMeda, Ghent University, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arterial compliance (C) is related to the elasticity, size, and geometrical distribution of arteries. Compliance is a determinant of the load that impedes ventricular ejection. Measuring compliance is difficult, particularly in the pulmonary circulation in which resistive and compliant vessels overlap. Comparing different methods for quantification of compliance to a method that involves a continuous flow might help to identify the optimal method. Pulmonary arterial compliance was computed in six pigs based on the stroke volume to pulse pressure ratio, diastolic decay exponential fitting, area method, and the pulse pressure method (PPM). Compliance measurements were compared to those obtained under continuous flow conditions through a right ventricular bypass (Heartware Inc., Miami Lakes, FL, USA). Compliance was computed for various flows using diastolic decay exponential fitting after an abrupt interruption of the pump. Under the continuous flow conditions, resistance (R) was a decreasing function of the flow, and the fitting to P = e

Indexed as

elasticityheart-assist devicepulmonary circulation

Identifiers

PMID29708019
PMCPMC5960867

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.