Evidence map›Paper›PMID 29707859›Full record

ArticleAddiction (Abingdon, England)2018

Does early exposure to caffeine promote smoking and alcohol use behavior? A prospective analysis of middle school students.

Alfgeir L Kristjansson, Steven M Kogan, Michael J Mann, Megan L Smith, Laura M Juliano, Christa L Lilly, Jack E James

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. Caffeine, Daytime Sleepiness, and Conduct Problems Among Early Adolescents: A Longitudinal Analysis.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
    Article
  4. Predicting Genetic Risk for Impulsivity and Substance Use in Adolescence.medRxiv : the preprint server for health sciences · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alfgeir L KristjanssonDepartment of Social and Behavioral Sciences, School of Public Health, West Virginia University, Morgantown, WV, USA.ORCID http://orcid.org/0000-0001-8136-9210
Steven M KoganDepartment of Human Development and Family Science, University of Georgia, Athens, GA, USA.
Michael J MannDepartment of Social and Behavioral Sciences, School of Public Health, West Virginia University, Morgantown, WV, USA.
Megan L SmithDepartment of Social and Behavioral Sciences, School of Public Health, West Virginia University, Morgantown, WV, USA.
Laura M JulianoDepartment of Psychology, American University, Washington, DC, USA.
Christa L LillyDepartment of Biostatistics, School of Public Health, West Virginia University, Morgantown, WV, USA.
Jack E JamesDepartment of Psychology, Reykjavik University, Reykjavik, Iceland.

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Laura F. Gibson · 2012 to 2026
$81.0M
NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

BACKGROUND AND

aimsDespite the negative consequences associated with caffeine use among children and youth, its use is increasingly widespread among middle school students. Cross-sectional studies reveal links between caffeine and other substance use. The potential for caffeine use to confer increased vulnerability to substance use, however, has not been investigated using prospective designs. We hypothesized that caffeine use at baseline would be associated positively with increased alcohol use, drunkenness, smoking and e-cigarette use.

designProspective cohort study with 12 months separating baseline from follow-up.

settingWest Virginia, USA.

participantsMiddle school students (6th and 7th grades; n = 3932) in three West Virginia (WV) counties provided data at baseline and follow-up 12 months later. MEASUREMENTS: Youth self-reported their use of caffeine from multiple sources (e.g. soda, energy drinks, coffee and tea), cigarette smoking, electronic cigarette use, alcohol use and drunkenness.

findingsCross-lagged path models for individual substance use categories provided a good fit to the data. Controlling for demographic variables and other substance use at baseline, caffeine at time 1 (T1) was associated positively with T2 cigarette smoking (β = 0.27, P = 0.001), e-cigarette use (β = 0.21, P = 0.001), alcohol use (β = 0.17, P = 0.001) and drunkenness (β = 0.15, P = 0.001). Conversely, non-significant relations emerged between three of four substances at T1 and caffeine at T2. Positive relations were found between e-cigarette use at T1 and caffeine use at T2 (β = 0.07, P = 0.006). These findings were supported by an omnibus model with all substances included. Specifically, significant relations were observed between caffeine at T1 and all substance use outcomes at T2, whereas no significant relations were observed between substance use and caffeine over time.

conclusionsCaffeine may promote early use of other types of substances among middle school-aged adolescents.

Indexed as

Alcohol useAppalachiacaffeineearly adolescentsprimary preventionsmoking

Identifiers

PMID29707859
PMCPMC6207478

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.