Evidence map›Paper›PMID 29707622›Full record

ArticleTransplantation direct2018

Improved Health-Related Quality of Life in Older Kidney Recipients 1 Year After Transplantation.

Kjersti Lønning, Kristian Heldal, Tomm Bernklev, Cathrine Brunborg, Marit Helen Andersen, Nanna von der Lippe, Anna Varberg Reisæter, Pål-Dag Line, Anders Hartmann, Karsten Midtvedt

Registry-linked trialAbstract read
In one paragraph

Article in Transplantation direct, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01760733 (Improved Selection of Elderly), which is not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01760733 active not recruitingnot on this map

Improved Selection of Elderly (> 65 Years) for Kidney Transplantation

TypeobservationalSponsorSykehuset TelemarkRan2012 to 2030Enrolled289ConditionsQuality of Life, End Stage Renal Disease, End Stage Renal Failure on Dialysis
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Mapping health-related quality of life after kidney transplantation by group comparisons: a systematic review.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021
    Pooled it
  3. Article
  4. Article
  5. Kidney Transplantation Improves Health-Related Quality of Life in Older Recipients.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  6. Article
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  8. Living Donor Kidney Transplantation in Older Individuals: An Ethical Legal and Psychological Aspects of Transplantation (ELPAT) View.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
  9. Article
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  11. Article
  12. Inequitable Access to Transplants: Adults With Impaired Decision-Making Capacity.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kjersti LønningDepartment of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
Kristian HeldalFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Tomm BernklevFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Cathrine BrunborgOslo Centre for Biostatistics and Epidemiology, Research Support Services, Oslo University Hospital, Oslo, Norway.
Marit Helen AndersenDepartment of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
Nanna von der LippeFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Anna Varberg ReisæterDepartment of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
Pål-Dag LineDepartment of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
Anders HartmannDepartment of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.
Karsten MidtvedtDepartment of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to evaluate changes in health-related quality of life (HRQoL) in patients 65 years or older from time of kidney transplantation (KTx) until 1 year postengraftment.

methodsA single-center prospective study was conducted. HRQoL was measured pre-KTx and at 2, 6, and 12 months postengraftment using self-reported Kidney Disease and Quality of Life short-form version 1.3. Intraindividual scores before and after KTx were evaluated. Liu Comorbidity Index was registered at enlisting. short-form-36 scores were additionally compared with scores from an age-matched population.

resultsFrom January 1, 2013, until November 30, 2016, a total of 289 waitlisted patients were included. By September 1, 2017, 134 had reached 1 year postengraftment, and valid questionnaires were available in 120 (90%) patients. Mean age at KTx was 71.6 years (±4.3 years), 71% were male. Living donor was used in 21%, and preemptive KTx was performed in 30% of the recipients. Median waiting time for KTx from deceased donor was 16 months (range, 0.6-50.5 months). A total of 79 (66%) recipients had a Liu Comorbidity Index score of 3 or less.All HRQoL scores except the domain social function improved at 2 months postengraftment and remained stable or continued to improve at 1 year.HRQoL scores 12 months postengraftment were similar to those described in an age-matched general population except for the domain social function which remained at a significantly lower level. Time in dialysis was the most important variable associated with impaired HRQoL postengraftment.

conclusionsHRQoL scores showed clinically significant improvement in older KTx recipients 1 year posttransplant.

Identifiers

PMID29707622
PMCPMC5908461

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.