Evidence map›Paper›PMID 29707581›Full record

SynthesisBioMed research international2018

An Overview of Meta-Analyses of Endovascular Bridging Therapies for Acute Ischemic Stroke.

Si-Yan Chen, Xing-Ru Zhang, Jie Chen, Wan-Qian Ge, Wen-Wen Wang, Xin-Shi Wang, Cheng-Long Xie

Open access · hybridAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Si-Yan ChenDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Xing-Ru ZhangDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Jie ChenDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Wan-Qian GeDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Wen-Wen WangThe Center of Traditional Chinese Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325027, China.
Xin-Shi WangDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.ORCID 0000-0002-1742-5422
Cheng-Long XieDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.ORCID 0000-0002-1132-0179
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute Ischemic Stroke (AIS) is a common cause of death worldwide and the leading cause of long-term severe disability. Endovascular bridging therapies (EBT), including endovascular thrombectomy (ET) and intra-arterial thrombolytic (IAT), have been recommended to realize a favorable functional outcome for AIS patients.

methodsAn overview of meta-analyses of primary randomized controlled trial (RCT) studies was performed evaluating EBT for AIS patients compared with usual care.

resultsTen meta-analyses were included in this overview. ET was associated with a higher incidence of achieving functional outcome improvement, defined as a modified Rankin scale of 0 to 1 (mRS,

conclusionsIn conclusion, our analysis supports that EBT, regardless of format (e.g., ET or IAT), is superior to the best medical therapy alone (e.g., IVT) in terms of mRS score in patients with AIS. In addition, the safety of EBT is similar to IVT.

Indexed as

Acute DiseaseBrain IschemiaEndovascular ProceduresHumansMechanical ThrombolysisRandomized Controlled Trials as TopicStrokeThrombectomy

Identifiers

PMID29707581
PMCPMC5863300
OpenAlexW2790836874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.