Evidence map›Paper›PMID 29707531›Full record

ArticleFrontiers in pediatrics2018

Morphometric Magnetic Resonance Imaging Study in Children With Primary Monosymptomatic Nocturnal Enuresis.

Mengxing Wang, Anyi Zhang, Jilei Zhang, Haifeng Lu, Shuai Xu, Zhaoxia Qin, Jun Ma, Xiaoxia Du

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  6. Pathogenesis and brain functional imaging in nocturnal enuresis: A review.Experimental biology and medicine (Maywood, N.J.) · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Mengxing WangShanghai Key Laboratory of Magnetic Resonance, Department of Physics, School of Physics and Materials Science, East China Normal University, Shanghai, China.
Anyi ZhangDepartment of Developmental and Behavioral Pediatrics, Shanghai Institute of Pediatric Translational Medicine, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jilei ZhangShanghai Key Laboratory of Magnetic Resonance, Department of Physics, School of Physics and Materials Science, East China Normal University, Shanghai, China.
Haifeng LuShanghai Key Laboratory of Magnetic Resonance, Department of Physics, School of Physics and Materials Science, East China Normal University, Shanghai, China.
Shuai XuShanghai Key Laboratory of Magnetic Resonance, Department of Physics, School of Physics and Materials Science, East China Normal University, Shanghai, China.
Zhaoxia QinShanghai Key Laboratory of Magnetic Resonance, Department of Physics, School of Physics and Materials Science, East China Normal University, Shanghai, China.
Jun MaDepartment of Developmental and Behavioral Pediatrics, Shanghai Institute of Pediatric Translational Medicine, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiaoxia DuShanghai Key Laboratory of Magnetic Resonance, Department of Physics, School of Physics and Materials Science, East China Normal University, Shanghai, China.
East China Normal University · CNShanghai Children's Medical Center · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePrimary monosymptomatic nocturnal enuresis (PMNE) refers to bed-wetting in children who have no other lower urinary tract symptoms and are never dry for more than 6 months. Our previous studies demonstrated that children with PMNE exhibited brain functional abnormalities compared with healthy controls; however, researches on the abnormalities in gray matter were limited. This study aimed to investigate brain structural changes in gray matter of children with PMNE using magnetic resonance imaging (MRI).

methodsGray matter volumes (GMVs) and gyrification indices (GIs) were calculated using voxel-based and surface-based morphometry analyses of structural MRI data acquired from 26 children with PMNE and 28 healthy children. To identify between-group differences in gray matter, two-sample

resultsCompared with the controls, children with PMNE showed significantly increased GMVs in the supplementary motor area and medial prefrontal cortex regions (mean GMV in PMNE: 0.54 ± 0.07 l; mean GMV in controls: 0.50 ± 0.06 l) and reduced GIs in the right precuneus (mean GI in PMNE: 25.74° ± 2.34°; mean GI in controls: 27.97° ± 1.79°).

conclusionChildren with PMNE showed abnormal GMVs in frontal lobe and GIs in precuneus, and these changes might be involved in the pathological mechanism of PMNE.

Indexed as

magnetic resonance imagingnocturnal enuresisprecuneusstructural changesupplementary motor area

Identifiers

PMID29707531
PMCPMC5908894
OpenAlexW2797266905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.