ReviewFrontiers in pediatrics2018
Treating Hypotension in Preterm Neonates With Vasoactive Medications.
Review in Frontiers in pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Comparative efficacy of volume expansion, inotropes and vasopressors in preterm neonates with probable transitional circulatory instability in the first week of life: a systematic review and network meta-analysis.BMJ paediatrics open · 2024Pooled it
- Impact of Implementing a Standardized Neonatal Blood Pressure Chart and Neonatal Hypotension Management Guidelines in the Neonatal Intensive Care Unit: A Retrospective Cohort Study.American journal of perinatology · 2026Article
- Clinical and echocardiographic response to volume expansion in hypotensive preterm infants: a pilot observational study.Frontiers in pediatrics · 2026Article
- In vivo and ex vivo cardiovascular haemodynamic responses of preterm growth-restricted lambs to perinatal asphyxia.Clinical science (London, England : 1979) · 2025Article
- Outcome of Preterm Neonates > 32 Weeks Gestation in Relation to Three-Tiered Fetal Heart Rate Categorization.Medicina (Kaunas, Lithuania) · 2025Article
- An Update on Pharmacologic Management of Neonatal Hypotension: When, Why, and Which Medication.Children (Basel, Switzerland) · 2024Review
- Blood pressure trends following birth in infants born under 25 weeks' gestational age: a retrospective cohort study.BMJ paediatrics open · 2024Observational
- Prognostic accuracy of Neonatal SOFA score versus SIRS criteria in preterm infants with late-onset sepsis.European journal of pediatrics · 2023Article
- Dopamine or norepinephrine for sepsis-related hypotension in preterm infants: a retrospective cohort study.European journal of pediatrics · 2023Article
- Congenital Diaphragmatic Hernia: Perinatal Prognostic Factors and Short-Term Outcomes in a Single-Center Series.Children (Basel, Switzerland) · 2023Article
- Bioreactance-derived haemodynamic parameters in the transitional phase in preterm neonates: a longitudinal study.Journal of clinical monitoring and computing · 2022Observational
- Misoprostol treatment prevents hypoxia-induced cardiac dysfunction through a 14-3-3 and PKA regulatory motif on Bnip3.Cell death & disease · 2021Article
- Hypothyroxinaemia in refractory shock: a clue to diagnose hypopituitarism.BMJ case reports · 2021Article
- Prenatal duct closure leading to severe pulmonary hypertension in a preterm neonate-a case report.Cardiovascular diagnosis and therapy · 2020Article
- Severe Hyponatraemia Associated with the Use of Arginine-Vasopressin in Two Neonates with Complex Congenital Heart Disease.Journal of pediatric intensive care · 2020Article
- Systematic Review and Meta-Analysis of Cardiovascular Medications in Neonatal Hypotension.Biomedicine hubArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preterm neonates often have hypotension which may be due to various etiologies. While it is controversial to define hypotension in preterm neonates, various vasoactive medications are commonly used to provide the cardiovascular support to improve the blood pressure, cardiac output, or to treat shock. However, the literature on the systemic and regional hemodynamic effects of these antihypotensive medications in neonates is deficient and incomplete, and cautious translation of findings from other clinical populations and animal studies is required. Based on a literature search on published reports, meta-analytic reviews, and selected abstracts, this review discusses the current available information on pharmacologic actions, clinical effects, and side effects of commonly used antihypotensive medications including dopamine, dobutamine, epinephrine, norepinephrine, vasopressin, and milrinone in preterm neonates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.