ArticlePeerJ2018
Association between vitamin D concentrations and knee pain in patients with osteoarthritis.
Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Article
- The association of vitamin D with knee osteoarthritis pain: an analysis from the Osteoarthritis Initiative database.Scientific reports · 2024Article
- Current Evidence on and Clinical Implications of Vitamin D Levels in Pain and Functional Management of Knee Osteoarthritis: A Systematic Review.Clinics and practice · 2024Review
- Vitamin D and its association with symptom severity in knee osteoarthritis: a cross sectional study at a national referral hospital in Uganda.BMC rheumatology · 2021Article
- Association of Serum Vitamin D with Serum Cytokine Profile in Patients with Knee Osteoarthritis.Cartilage · 2021Article
- The Role of Vitamin D in Early Knee Osteoarthritis and Its Relationship with Their Physical and Psychological Status.Nutrients · 2021Article
- Article
- The effectiveness of vitamin D supplementation in functional outcome and quality of life (QoL) of lumbar spinal stenosis (LSS) requiring surgery.Journal of orthopaedic surgery and research · 2020Article
- Relationship between Vitamin D levels and pain and disease activity in patients with newly diagnosed axial spondyloarthritis.International journal of nursing sciences · 2020Article
- Association between serum Vitamin D deficiency and Knee Osteoarthritis.Mediterranean journal of rheumatology · 2019Article
- Therapeutic and Preventive Potential of Vitamin D Supplementation in Knee Osteoarthritis.ACR open rheumatology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesOsteoarthritis (OA) and vitamin D deficiency are common health conditions in older people. Whether vitamin D concentration is associated with knee OA is controversial. In this study, we aimed to determine the association between serum concentrations of vitamin D and osteoarthritic knee pain. SUBJECTS AND
methodsVitamin D concentrations were measured with the 25 hydroxyvitamin D test in patients presenting with clinical symptoms of primary knee osteoarthritis. Osteoarthritis was graded on the Kellgren-Lawrence grading scale from anteroposterior and lateral radiographs. Height, weight, and body mass index (BMI) were recorded. Patients completed a 10-cm visual analogue scale (VAS) for indicating pain and the Western Ontario and McMaster Universities Arthritis Index (WOMAC). Vitamin D concentration was defined as severely deficient (<10 ng/mL), insufficient (10 to 19 ng/mL), or normal (20 to 50 ng/mL).
resultsOf 149 patients (133 women), the mean age was 63.6 years. Mean vitamin D concentration was 11.53 ng/mL, and 90% patients were vitamin D deficient. Mean WOMAC score was 57.2, and VAS pain score was 7.5. Kellgren-Lawrence grade was 2 for 10 patients, grade 3 for 61, and grade 4 for 88. Mean BMI was 33.4. Mean values of VAS, WOMAC, and BMI did not differ by vitamin D status.
conclusionSerum vitamin D concentration is not associated with knee pain in patients with osteoarthritis.
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