Evidence map›Paper›PMID 29707392›Full record

ArticleCardiology research and practice2018

Cardiovascular Risk Assessment in a Cohort of Newly Diagnosed Patients with Obstructive Sleep Apnea Syndrome.

Kostas Archontogeorgis, Athanasios Voulgaris, Evangelia Nena, Maria Strempela, Panagiota Karailidou, Argyrios Tzouvelekis, Toulin Mouemin, Maria Xanthoudaki, Stylianos Steiropoulos, Marios E Froudarakis and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cardiology research and practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

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  12. Adiponectin Relieves Human Adult Cardiac Myocytes Injury Induced by Intermittent Hypoxia.Medical science monitor : international medical journal of experimental and clinical research · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Kostas ArchontogeorgisMSc Program in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
Athanasios VoulgarisMSc Program in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.ORCID 0000-0003-3486-8855
Evangelia NenaLaboratory of Hygiene and Environmental Protection, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.ORCID 0000-0003-0381-4715
Maria StrempelaMSc Program in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
Panagiota KarailidouMSc Program in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
Argyrios TzouvelekisDivision of Immunology, Biomedical Sciences Research Center "Alexander Fleming", Athens, Greece.
Toulin MoueminDepartment of Pneumonology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
Maria XanthoudakiDepartment of Pneumonology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
Stylianos Steiropoulos1st Cardiology Department, General Hospital of Nikea "Agios Panteleimon", Nikea, Greece.
Marios E FroudarakisDepartment of Pneumonology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
Paschalis SteiropoulosMSc Program in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.ORCID 0000-0001-7121-6253
Democritus University of Thrace · GRAlexander Fleming Biomedical Sciences Research Center · GRGeneral Hospital of Nikea · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesObstructive sleep apnea syndrome (OSAS) is associated with increased cardiovascular morbidity and mortality. The aim of this study was to assess whether the 10-year risk for cardiovascular disease in newly diagnosed patients with OSAS is increased. MATERIALS AND

methodsRecently diagnosed, with polysomnography, consecutive OSAS patients were included. The Systematic Coronary Risk Evaluation (SCORE) and the Framingham Risk Score (FRS) were used to estimate the 10-year risk for cardiovascular disease.

resultsTotally, 393 individuals (73.3% males), scheduled to undergo a polysomnographic study with symptoms indicative of OSAS, were enrolled. According to apnea-hypopnea index (AHI), subjects were divided in four groups: mild OSAS (AHI 5-14.9/h) was diagnosed in 91 patients (23.2%), moderate OSAS (AHI 15-29.9/h) in 58 patients (14.8%), severe OSAS (AHI > 30/h) in 167 patients (42.5%), while 77 individuals (19.6%) had an AHI < 5/h and served as controls. Increased severity of OSAS was associated with increased SCORE (

conclusionsThe 10-year risk for cardiovascular morbidity and mortality seems to increase with severity of OSAS. Physicians should bear this finding in mind, in order to seek for and consecutively eliminate risk factors for cardiovascular disease and to prevent future cardiovascular events in OSAS patients.

Identifiers

PMID29707392
PMCPMC5863345
OpenAlexW2791046190

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.