Evidence map›Paper›PMID 29707341›Full record

ArticleJournal of thoracic disease2018

Short-term one-lung ventilation does not influence local inflammatory cytokine response after lung resection.

Silvia Fiorelli, Veronica Defraia, Fabiola Cipolla, Cecilia Menna, Mohsen Ibrahim, Claudio Andreetti, Maurizio Simmaco, Monica Rocco, Erino Angelo Rendina, Marina Borro and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of thoracic disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Silvia FiorelliDepartment of Anesthesiology and Intensive Care, Sapienza University of Rome, Italy.
Veronica DefraiaDepartment of Anesthesiology and Intensive Care, Sapienza University of Rome, Italy.
Fabiola CipollaThe Department of Neurosciences, Mental Health and Sensory Organs (NESMOS), Sapienza University of Rome, Italy.
Cecilia MennaDepartment of Thoracic Surgery; Sapienza University of Rome, Italy.
Mohsen IbrahimDepartment of Thoracic Surgery; Sapienza University of Rome, Italy.
Claudio AndreettiDepartment of Thoracic Surgery; Sapienza University of Rome, Italy.
Maurizio SimmacoThe Department of Neurosciences, Mental Health and Sensory Organs (NESMOS), Sapienza University of Rome, Italy.
Monica RoccoDepartment of Anesthesiology and Intensive Care, Sapienza University of Rome, Italy.
Erino Angelo RendinaDepartment of Thoracic Surgery; Sapienza University of Rome, Italy.
Marina BorroThe Department of Neurosciences, Mental Health and Sensory Organs (NESMOS), Sapienza University of Rome, Italy.
Domenico MassulloDepartment of Anesthesiology and Intensive Care, Sapienza University of Rome, Italy.
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOne-lung ventilation (OLV) is a ventilation procedure used for pulmonary resection which may results in lung injury. The aim of this study was to evaluate the local inflammatory cytokine response from the dependent lung after OLV and its correlation to VT. The secondary aim was to evaluate the clinical outcome of each patient.

methodsTwenty-eight consecutive patients were enrolled. Ventilation was delivered in volume-controlled mode with a VT based on predicted body weight (PBW). 5 cmH

resultsCytokine BAL levels after surgery showed no significant increase after OLV, and no significant differences were recorded between the two subgroups. The mean duration of OLV was 64.44±21.68 minutes. No postoperative respiratory complications were recorded. The mean length of stay was for 4.00±1.41 days in the PV subgroup and 4.45±2.07 days in the CV group; no statistically significant differences were recorded between the two subgroups (P=0.511).

conclusionsLocalized inflammatory cytokine response after OLV was not influenced by the use of different VT. Potentially, the application of PEEP in both ventilation strategies and the short duration of OLV could prevent postoperative complications.

Indexed as

cytokinesinflammationOne-lung ventilation (OLV)thoracic surgery

Identifiers

PMID29707341
PMCPMC5906264
OpenAlexW2794306892

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.